15 products were found matching "Cay13717-100"!

15(R)-PGE1 is the "unnatural" C-15 stereoisomer of PGE1. It is essentially inactive biologically when compared to PGE1. It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC50 of 189 µM.Formal Name: 9-oxo-11alpha,15R-dihydroxy-prost-13E-en-1-oic acid. CAS Number: 20897-91-0. Synonyms: 15(R)-PGE1, 15-epi...

UR-144 N-(4-chloropentyl) analog is a synthetic cannabinoid that differs from the parent compound, UR-144 (Cay-ISO60055), by the addition of chloride to the 4 position of the pentyl chain. The physiological and toxicological properties of this compound have not been studied. This product is intended for forensic and...

Lysergol is an ergot alkaloid that has been found in S. sorghi and an agonist of the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, and 5-HT2C (EC50s = 73, 1.6, and 6.6 nM, respectively, in a FLIPR assay). It induces contractions in isolated rat tail arteries (EC50 = 436.5 nM). Lysergol (10 µg/ml) also enhances...

WB 1:500 - 1:2000. Protein function: Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo. [The UniProt Consortium]

JWH 073 4-hydroxyindole metabolite-d7 contains seven deuterium atoms at the 2, 2', 3, 3', 4, 4, and 4 positions. It is intended for use as an internal standard for the quantification of JWH 073 4-hydroxyindole metabolite by GC- or LC-mass spectrometry (MS). JWH 073 is a mildly selective agonist of the central...

Sophorose is a disaccharide component of the microbial glycolipids produced by yeast termed sophorolipids. Due to their hydrophobic nature, sophorolipids are often employed as biosurfactants. Sophorolipids also demonstrate antibacterial, antifungal, spermicidal, virucidal, and anti-cancer activities. Sophorose has...

BYK 191023 is an L-arginine competitive and selective inhibitor of inducible nitric oxide synthase (iNOS) with IC50 values of 0.086, 17, and 162 µM for human recombinant iNOS, nNOS, and eNOS, respectively. It also inhibits murine recombinant iNOS (IC50 = 95 nM). BYK 191023 inhibits iNOS-induced nitrite generation in...

Spiro-MeOTAD is a stable and efficient hole-transport material in organic light-emitting devices and in solid-state dye-sensitized solar cells (ssDSSCs). It yields higher ssDSSC efficiency compared to the liquid electrolyte for DSSC solar cells due to its reasonable charge carrier mobility and its amorphous nature...

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells and their main function is to...

A common metabolic pathway for several prostaglandins (PGs), including prostaglandin D2 (PGD2), involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the alpha-terminus and oxidation of the...

Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase). Presumably through these actions, it blocks the activation of T cells by allogeneic dendritic cells (IC50 = 0.55 nM) without affecting dendritic cells. Moreover,...

Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin (Cay-17161) meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP...