Anti-KIAA1598

Anti-KIAA1598
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-648A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A304-648A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Involved in the generation of internal asymmetric signals required for neuronal... more
Product information "Anti-KIAA1598"
Protein function: Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Mediates netrin-1-induced F-actin-substrate coupling or 'clutch engagement' within the axon growth cone through activation of CDC42, RAC1 and PAK1-dependent signaling pathway, thereby converting the F-actin retrograde flow into traction forces, concomitantly with filopodium extension and axon outgrowth. Plays a role in cytoskeletal organization by regulating the subcellular localization of phosphoinositide 3-kinase (PI3K) activity at the axonal growth cone. Plays also a role in regenerative neurite outgrowth. In the developing cortex, cooperates with KIF20B to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in the accumulation of phosphatidylinositol 3,4,5- trisphosphate (PIP3) in the growth cone of primary hippocampal neurons. [The UniProt Consortium]
Keywords: Anti-Shootin1, Anti-KIAA1598, Anti-Shootin-1
Supplier: Bethyl Laboratories
Supplier-Nr: A304-648A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: chimpanzee, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A304-648A maps to a region between residue 575 to 625 of human KIAA1598 using the numbering given in entry NP_001120683.1 (GeneID 57698).
Format: Antigen Affinity Purified

Database Information

UniProt ID : A0MZ66 | Matching products
Gene ID GeneID 57698 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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