Anti-KDM2B, NT (Lysine-specific Demethylase 2B, JmjC Domain-containing Histone Demethylation Protein

Anti-KDM2B, NT (Lysine-specific Demethylase 2B, JmjC Domain-containing Histone Demethylation Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
K0138-40B-Biotin.200 200 µl - -

3 - 19 business days*

993.00€
 
FBXL10 is a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby... more
Product information "Anti-KDM2B, NT (Lysine-specific Demethylase 2B, JmjC Domain-containing Histone Demethylation Protein"
FBXL10 is a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. It preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. FBXL10 is a member of the F-box protein family which is characterized by an approximately 40aa motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL10 belongs to the Fbls class. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Immunohistochemistry: 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-CXXC2, Anti-KDM2B, Anti-Protein JEMMA, EC=1.14.11.27, Anti-F-box protein FBL10, Anti-F-box/LRR-repeat protein 10, Anti-Lysine-specific demethylase 2B, Anti-CXXC-type zinc finger protein 2, Anti-Protein-containing CXXC domain 2
Supplier: United States Biological
Supplier-Nr: K0138-40B-Biotin

Properties

Application: ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide selected from the N-terminal region of human FBXL10a (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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