Anti-KDM2B, CT (Lysine-specific Demethylase 2B, JmjC Domain-containing Histone Demethylation Protein

Anti-KDM2B, CT (Lysine-specific Demethylase 2B, JmjC Domain-containing Histone Demethylation Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
K0138-40A-FITC.200 200 µl - -

3 - 19 business days*

993.00€
 
FBXL10 is a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby... more
Product information "Anti-KDM2B, CT (Lysine-specific Demethylase 2B, JmjC Domain-containing Histone Demethylation Protein"
FBXL10 is a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. It preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. FBXL10 is a member of the F-box protein family which is characterized by an approximately 40aa motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL10 belongs to the Fbls class. Applications: Suitable for use in FLISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Immunohistochemistry: 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-CXXC2, Anti-KDM2B, Anti-Protein JEMMA, EC=1.14.11.27, Anti-F-box protein FBL10, Anti-F-box/LRR-repeat protein 10, Anti-Lysine-specific demethylase 2B, Anti-CXXC-type zinc finger protein 2, Anti-Protein-containing CXXC domain 2
Supplier: United States Biological
Supplier-Nr: K0138-40A-FITC

Properties

Application: FLISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide selected from the C-terminal region of human FBXL10a and FBXL10b (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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