Anti-JARID1D/SMCY

Anti-JARID1D/SMCY
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-751A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A301-751A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3,... more
Product information "Anti-JARID1D/SMCY"
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes, in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks. [The UniProt Consortium]
Keywords: Anti-HY, Anti-H-Y, Anti-KDM5D, EC=1.14.11.-, Anti-Protein SmcY, Anti-Histone demethylase JARID1D, Anti-Histocompatibility Y antigen, Anti-Lysine-specific demethylase 5D, Anti-Jumonji/ARID domain-containing protein 1D
Supplier: Bethyl Laboratories
Supplier-Nr: A301-751A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: primates)
Immunogen: synthetic peptide. The epitope recognized by A301-751A-M maps to a region between residue 1490 and 1540 of human SMC (mouse) homolog, Y chromosome (jumonji, AT rich interactive domain 1D ) using the numbering given in entry NP_004644.2 (GeneID 8284).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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