Anti-JMJD2A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-CB6	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-JMJD2A Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-JMJD2A"

Anti-JMJD2A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with JMJD2A from other sources has not been determined. Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. [The UniProt Consortium]

Keywords:	Anti-KDM4A, Anti-JHDM3A, EC=1.14.11.-, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A, Anti-JmjC domain-containing histone demethylation protein 3A
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-CB6

Properties

Application:	ELISA, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	14 amino acid synthetic peptide from near the internal region of human JMJD2A.
Format:	Purified