Anti-JHDM1A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-476A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A301-476A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3,... more

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Product information "Anti-JHDM1A"

Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys- 36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. [The UniProt Consortium]

Keywords:	Anti-KDM2A, Anti-CXXC8, EC=1.14.11.27, Anti-F-box protein FBL7, Anti-F-box protein Lilina, Anti-F-box/LRR-repeat protein 11, Anti-Lysine-specific demethylase 2A, Anti-CXXC-type zinc finger protein 8, Anti-[Histone-H3]-lysine-36 demethylase 1A
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-476A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: mouse, rat, chicken, turkey, bovine, dog, horse, rabbit, guinea pig, swine, panda, orangutan, rhesus monkey, gorilla, chimpanzee, west indian ocean coelacanth, tasmanian devil, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-476A maps to a region between residue 1112 and 1162 of human JmjC domain-containing histone demethylation protein 1A using the numbering given in entry NP_036440.1 (GeneID 22992).
Format:	Antigen Affinity Purified