Anti-JARID1A/RBP2 IHC Antibody, affinity purifie (IHC)

Anti-JARID1A/RBP2 IHC Antibody, affinity purifie (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00479-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00479 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3,... more
Product information "Anti-JARID1A/RBP2 IHC Antibody, affinity purifie (IHC)"
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1. [The UniProt Consortium]
Keywords: Anti-KDM5A, Anti-RBBP-2, Anti-JARID1A, EC=1.14.11.-, Anti-Histone demethylase JARID1A, Anti-Lysine-specific demethylase 5A, Anti-Retinoblastoma-binding protein 2, Anti-Jumonji/ARID domain-containing protein 1A
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00479

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat, dog, horse, rabbit, guinea pig_10141, panda, orangutan, gorilla, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by IHC-00479 maps to a region between residue 1640 and 1690 of human Jumonji/ARID Domain-Containing Protein 1A/Retinoblastoma Binding Protein 2 Homolog 1 using the numbering given in entry NP_001036068.1 (GeneID 5927).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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