Anti-Interleukin 12 beta Chain (Interleukin 12b, Interleukin-12b, IL12b, IL-12b, Interleukin 12 p40,

Anti-Interleukin 12 beta Chain (Interleukin 12b, Interleukin-12b, IL12b, IL-12b, Interleukin 12 p40,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
I8434-27D.100 100 µg - -

3 - 19 business days*

675.00€
 
IL-12 is a heterodimer composed of subunits IL-12A p35 and IL-12B p40. Autocrine IL-12 is... more
Product information "Anti-Interleukin 12 beta Chain (Interleukin 12b, Interleukin-12b, IL12b, IL-12b, Interleukin 12 p40,"
IL-12 is a heterodimer composed of subunits IL-12A p35 and IL-12B p40. Autocrine IL-12 is responsible for the differentiation of naive CD4+T cells into type 1 helper T cells (Th1) that produce interferon-_ (IFN-_). Expression of STAT 4, a signal transduction molecule important in cytokine-induced gene expression, appears central to IL-12 induced Th1 production of IFN-_. It also activates production of tumor necrosis factor (TNF) from T and natural killer cells. IL-12 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:4000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-IL-12B, Anti-IL-12 subunit p40, Anti-Interleukin-12 subunit beta, Anti-Cytotoxic lymphocyte maturation factor 40 kDa subunit
Supplier: United States Biological
Supplier-Nr: I8434-27D

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: mouse, rat
Immunogen: Synthetic peptide corresponding to C-EARQQNKYENYS from the internal region of mouse Il12b/Il12p40 (NP_032378.1).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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