IL-12 R-beta1 is a type I transmembrane protein belonging to the type I cytokine family of receptors. It binds to IL-12 with low affinity. The functional high-affinity IL-12 receptor is a complex of IL-12 R-beta1 and IL-12 R-beta2. Applications: Suitable for use in Flow Cytometry. Other applications not tested....

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably...