24 products were found matching "I7661-23Y.50"!

Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). This protein can activate PI3K either...

Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this...

DNA sequences encoding the extracellular domain of human Integrin alpha M (Phe 17-Asn 1104, Accession# P11215) (Corbi, A.L., et al., 1988, J. Biol. Chem. 263:12403) with an acid tail at the C-terminus and the extracellular domain of human Integrin b2 (Gln 22-Asn 700, Accession# P05107) (Kishimoto, T. et al., 1987,...

Applications: , Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (FFPE): 10ug/ml Requires HIER using sodium citrate buffer pH6.0 prior to staining., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for...

Applications:, Suitable for use in Immunohistochemistry and Immunofluorescence. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:200, Immunohistochemistry (PAP or ABC): 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at...

Applications: , Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12...

Integrin alphaLbeta2 is one of three beta2 integrin adhesion proteins. The non-covalent heterodimer of 180kD aL/CD11a and 95kD b2/CD18 integrin subunits is expressed on virtually all leukocytes. The ligand binding site of LFA-1 is in the N-terminal head region, formed by an interaction of the vWFA (I, I-like)...

Integrin alpha V beta 3 was purified from human placenta by affinity chromatography using immobilized monoclonal antibodies to alpha V beta 3 integrin. A tissue detergent extract, which was applied to the column was prepared as previously described (1). It has tested negative for HIV & Hepatitis. Applications:...

Integrin a11B1 is a noncovalent, heterdimeric collagen receptor that contains a 150kD a11 subunit complexed to a 130kD B1/CD29 subunit. a11B1 is the only known a11-containing integrin. By contrast, at least twelve a-integrins share the B1 subunit. a11B1 is expressed on fibroblasts from cornea, skin and periodontal...

Applications: , Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin sections): 10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid...

Integrin beta5 is a 100-110kD type I transmembrane glycoprotein that forms a non-disulfide-linked heterodimer with Integrin alphaV. Integrin alphaVbeta5 is a receptor for vitronectin that is expressed on a wide variety of cell types including keratinocytes, fibroblasts, adhesive monocytes, and select endothelium....

CD29 is a 130kD protein, also known as integrin b1, VLA-b chain, or GPIIa. It is a member of the integrin family, expressed broadly on leukocytes, endothelial cells, smooth muscle, and epithelial cells. In association with CD49a-f, CD29 forms the VLA-1 through VLA-6 complexes, respectively. It plays an important...