- Search results for Cay10011426-50
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7 products were found matching "Cay10011426-50"!
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Item number: Cay10011620-50
Raloxifene is a selective estrogen receptor modulator (SERM) that binds to the estrogen receptor with an IC50 value of 0.4 nM. It exhibits estrogenic activity in bone cells without stimulating breast or uterine tissues. Raloxifene guards endothelial cells obtained from rat aortic rings against oxidative insult (1...
Keywords: | Keoxifene, LY156758, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone,... |
Application: | Estrogen receptor modulator |
CAS | 82640-04-8 |
MW: | 510 D |
From 43.00€
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Item number: Cay10011450-10
MRS2179 is a competitive purinergic P2Y1 receptor antagonist (Kb = 102 nM). It is selective for P2Y1 over P2Y2, P2Y4, P2Y6, P2Y12, and P2Y13, as well as P2X1-4, receptors at 10 µM. MRS2179 reduces phospholipase C (PLC) activity induced by the P2Y receptor agonist 2-methylthioadenosine diphosphate (2-MeSADP,...
Keywords: | 2'-deoxy-N-methyl-3'-adenylic acid, 5'-(dihydrogen phosphate), ammonium salt, hydrate |
Application: | Competitive P2Y1 receptor antagonist |
MW: | 425.2 D |
From 54.00€
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Item number: Cay10011246-5
Janus kinase 3 (JAK3) is a cytoplasmic protein tyrosine kinase that functions in the initiation of cytokine-triggered signal transduction by catalyzing the phosphorylation of signal transduction and activators of transcription (STATs). JAK3 is abundantly expressed in normal lymphoid cells as well as human...
Keywords: | Janex 1, 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
Application: | JAK3 inhibitor |
CAS | 202475-60-3 |
MW: | 297.3 D |
From 42.00€
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Item number: Cay10011264-5
Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. CAY10578 is a potent inhibitor of CK2 with an...
Keywords: | 4,5,6,7-tetraiodo-1,3-dioxo-2-isoindolineacetic acid |
Application: | CK2 inhibitor |
CAS | 19231-60-8 |
MW: | 708.8 D |
From 24.00€
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Item number: Cay10011206-5
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Keywords: | 3-oxo-C8-HSL, N-beta-oxo-octanoyl-L-Homoserine lactone, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide |
Application: | Antibiotic |
CAS | 147795-39-9 |
MW: | 241.3 D |
From 52.00€
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Item number: Cay10011256-50
Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis and its activity is increased in many proliferating tissues and tumors, which lends promise as an anti-cancer drug target. CAY10577 inhibits CK2 with an...
Keywords: | 7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
Application: | CK2 inhibitor |
CAS | 300675-28-9 |
MW: | 258.1 D |
From 24.00€
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Item number: Cay10010426-5
KRP 203 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist. It selectively induces calcium mobilization in CHO-K1 cells expressing mouse S1P1 over mouse S1P3 and S1P4 (EC50s = 0.84, >1,000, and 9.61 nM, respectively). In vivo, KRP 203 (0.3 mg/kg) prevents the development of wasting syndrome, decreases diarrhea...
Keywords: | Mocravimod (hydrochloride), 2-amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol,... |
Application: | S1P1 receptor agonist |
CAS | 509088-69-1 |
MW: | 480.4 D |
From 68.00€
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