- Search results for Cay15482-25
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4 products were found matching "Cay15482-25"!
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Item number: Cay15422-5
Carbamazepine is an inhibitor of sodium channels. It preferentially inhibits inactivated voltage-gated sodium channel Nav1.7 and Nav1.3 (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM,...
Keywords: | CBZ, NSC 169864, 5H-dibenz[b,f]azepine-5-carboxamide |
Application: | Voltage-gated sodium channel blocker |
CAS | 298-46-4 |
MW: | 236.3 D |
From 35.00€
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Item number: Cay15425-25
Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 14 nM, IC50 = 1.8 µM), which is the main receptor responsible for ADP-induced platelet aggregation. It functions by directly changing the conformation of the P2Y12 receptor to inhibit ADP binding. Formulations containing ticagrelor...
Keywords: | AR-C 126532XX, AZD 6140,... |
Application: | P2Y12 receptor antagonist |
CAS | 274693-27-5 |
MW: | 522.6 D |
From 43.00€
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Item number: Cay15248-250
9-Phenanthrol is an inhibitor of transient receptor potential melastatin 4 (TRPM4, IC50s = 19.1, 17.1, and 22.8 µM at +40, -40, and -80 mV, respectively, in HEK293 cells expressing the human receptor). It is selective for TRPM4 over TRPM5 at 100 µM. 9-Phenanthrol (100 µM) reduces heart rate in spontaneously beating...
Keywords: | 9-Hydroxyphenanthrene, NSC 50554 |
Application: | TRPM4 inhibitor |
CAS | 484-17-3 |
MW: | 194.2 D |
From 66.00€
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Item number: Cay15428-25
Lamotrigine is an anticonvulsant. It inhibits voltage-gated sodium channels (Nav) in HEK293 cells expressing recombinant human Nav1.2, Nav1.5, or Nav1.8 (IC50s = 10, 62, and 96 µM, respectively), as well as high voltage-activated calcium currents in isolated rat cortical neurons (IC50 = 12.3 µM), an effect that can...
Keywords: | BW 430C, Epilepax, Lamictal, LTG, 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine |
Application: | Voltage-gated sodium channel inhibitor |
CAS | 84057-84-1 |
MW: | 256.1 D |
From 77.00€
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