5 products were found matching "Cay10011421-50"!
No results were found for the filter!
MRS2179 (ammonium salt hydrate)
Item number: Cay10011450-10
MRS2179 is a competitive purinergic P2Y1 receptor antagonist (Kb = 102 nM). It is selective for P2Y1 over P2Y2, P2Y4, P2Y6, P2Y12, and P2Y13, as well as P2X1-4, receptors at 10 µM. MRS2179 reduces phospholipase C (PLC) activity induced by the P2Y receptor agonist 2-methylthioadenosine diphosphate (2-MeSADP,...
| Keywords: | 2'-deoxy-N-methyl-3'-adenylic acid, 5'-(dihydrogen phosphate), ammonium salt, hydrate |
| Application: | Competitive P2Y1 receptor antagonist |
| MW: | 425.2 D |
From 54.00€
*
Trimidox (hydrochloride)
Item number: Cay10011124-50
Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in...
| Keywords: | CF 233 (hydrochloride), N,3,4,5-tetrahydroxy-benzenecarboximidamide, monohydrochloride |
| Application: | Ribonucleotide reductase inhibitor |
| CAS | 95933-75-8 |
| MW: | 220.6 D |
From 86.00€
*
N-decanoyl-L-Homoserine lactone
Item number: Cay10011201-5
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expression of specific target genes, such as transcriptional regulators...
| Keywords: | C10-HSL, N-[3S)-tetrahydro-2-oxo-3-furanyl]-decanamide |
| Application: | Bioactive lipid assays |
| CAS | 177315-87-6 |
| MW: | 255.4 D |
From 60.00€
*
Zaprinast
Item number: Cay10010421-250
The cyclic nucleotide second messenger guanosine 3'5'-cyclic monophosphate (cGMP) is an important mediator of signal transduction and hence a wide range of cellular processes. It can be generated by soluble guanylyl cyclase in response to binding of nitric oxide and degraded via members of the phosphodiesterase...
| Keywords: | 2-(o-Propoxyphenyl)-8-azapurin-6-one, M&B 22,948, 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one |
| Application: | PDE inhibitor |
| CAS | 37762-06-4 |
| MW: | 271.3 D |
From 38.00€
*
Actinomycin D
Item number: Cay11421-50
Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low...
| Keywords: | Cosmegen, Dactinomycin, Meractinomycin, NCI C04682, NSC 3053, Oncostatin K,... |
| Application: | Cancer studies, antineoplastic |
| CAS | 50-76-0 |
| MW: | 1255.5 D |
From 90.00€
*
