- Search results for Cay10011422-50
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4 products were found matching "Cay10011422-50"!
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Item number: Cay10011450-10
MRS2179 is a competitive purinergic P2Y1 receptor antagonist (Kb = 102 nM). It is selective for P2Y1 over P2Y2, P2Y4, P2Y6, P2Y12, and P2Y13, as well as P2X1-4, receptors at 10 µM. MRS2179 reduces phospholipase C (PLC) activity induced by the P2Y receptor agonist 2-methylthioadenosine diphosphate (2-MeSADP,...
Keywords: | 2'-deoxy-N-methyl-3'-adenylic acid, 5'-(dihydrogen phosphate), ammonium salt, hydrate |
Application: | Competitive P2Y1 receptor antagonist |
MW: | 425.2 D |
From 54.00€
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Item number: Cay10011250-25
NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria. In bacteria, NH125 inhibits several histidine kinases, inhibiting YycG with an IC50 of 6.6 µM. NH125 also decreases the viability of several cancer cell lines with IC50 values ranging from 0.7-4.7 µM. In mammalian cells, NH125...
Keywords: | 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide |
Application: | eEF-2K inhibitor |
CAS | 278603-08-0 |
MW: | 524.6 D |
From 54.00€
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Item number: Cay10010421-250
The cyclic nucleotide second messenger guanosine 3'5'-cyclic monophosphate (cGMP) is an important mediator of signal transduction and hence a wide range of cellular processes. It can be generated by soluble guanylyl cyclase in response to binding of nitric oxide and degraded via members of the phosphodiesterase...
Keywords: | 2-(o-Propoxyphenyl)-8-azapurin-6-one, M&B 22,948, 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one |
Application: | PDE inhibitor |
CAS | 37762-06-4 |
MW: | 271.3 D |
From 38.00€
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Item number: Cay10010422-5
Nilotinib is an inhibitor of wild-type and mutant Bcr-Abl (IC50s = 15 and 9-400 nM, respectively). It is selective for wild-type and mutant Bcr-Abl over Src and LYN (IC50s = >5,000 nM for both). Nilotinib inhibits Bcr-Abl autophosphorylation and cell proliferation in Ba/F3 cells expressing wild-type or mutant...
Keywords: | AMN107,... |
Application: | Bcr inhibitor, Abl inhibitor |
CAS | 641571-10-0 |
MW: | 529.5 D |
From 34.00€
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