- Search results for Cay10011429-50
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4 products were found matching "Cay10011429-50"!
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Item number: Cay10011450-10
MRS2179 is a competitive purinergic P2Y1 receptor antagonist (Kb = 102 nM). It is selective for P2Y1 over P2Y2, P2Y4, P2Y6, P2Y12, and P2Y13, as well as P2X1-4, receptors at 10 µM. MRS2179 reduces phospholipase C (PLC) activity induced by the P2Y receptor agonist 2-methylthioadenosine diphosphate (2-MeSADP,...
Keywords: | 2'-deoxy-N-methyl-3'-adenylic acid, 5'-(dihydrogen phosphate), ammonium salt, hydrate |
Application: | Competitive P2Y1 receptor antagonist |
MW: | 425.2 D |
From 54.00€
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Item number: Cay10011249-50
CAY10576 is a multi-kinase inhibitor. It inhibits TANK-binding kinase 1 (TBK1), polo-like kinase 1 (Plk1), and IKKbeta (IC50s =0.093, 0.63, and 0.79 µM, respectively) and is selective for these kinases over IKKepsilon, Aurora B kinase, and cyclin-dependent kinase 2 (Cdk2, IC50s = 5, >5.32 and >30 µM, respectively)....
Keywords: | 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile |
Application: | IKKepsilon inhibitor |
CAS | 862812-98-4 |
MW: | 469.5 D |
From 61.00€
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Item number: Cay10011490-50
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 = 10-50 nM), both isoforms of PP2A (IC50 = 0.5 nM) and PP3 (IC50 = 4 nM). It is a very weak inhibitor of PP2B (IC50 > 2 µM) and does...
Keywords: | 35-demethyl DTX1, Acanthifolicin, NSC 677083, OA,... |
Application: | PP1 PP2A PP3 inhibitor |
CAS | 78111-17-8 |
MW: | 805 D |
From 77.00€
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Item number: Cay10011925-50
JNJ-7777120 is a potent and selective histamine H4 receptor antagonist, with a Ki value of approximately 4 nM against the human, mouse, and rat H4 receptors. Its Ki values for the histamine H1-3 receptors exceed 1 µM, regardless of species, and it has no or negligible effects on a range of other receptors and...
Keywords: | (5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-methanone |
Application: | Histamine H4 receptor antagonist |
CAS | 459168-41-3 |
MW: | 277.8 D |
From 27.00€
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