Anti-HSP60

Anti-HSP60
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-844A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A302-844A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: Chaperonin implicated in mitochondrial protein import and macromolecular... more
Product information "Anti-HSP60"
Protein function: Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable). [The UniProt Consortium]
Keywords: Anti-Hsp60, Anti-CPN60, Anti-HSP60, Anti-HSPD1, Anti-HSP-60, Anti-HuCHA60, EC=3.6.4.9, Anti-Chaperonin 60, Anti-60 kDa chaperonin, Anti-Heat shock protein 60, Anti-P60 lymphocyte protein, Anti-Mitochondrial matrix protein P1
Supplier: Bethyl Laboratories
Supplier-Nr: A302-844A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, chicken, bovine, orangutan)
Immunogen: synthetic peptide. The epitope recognized by A302-844A maps to a region between residue 50 and 100 of human Heat Shock Protein 60 using the numbering given in entry NP_002147.2 (GeneID 3329).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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