8 products were found matching "Cay10347-1"!
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12-Lipoxygenase (platelet-type, mouse recombinant)
Item number: Cay10341-25
12-Lipoxygenase (12-LO) catalyzes the formation of 12-HpETE from arachidonic acid. There are two main types of 12-LO, platelet-type and leukocyte-type, which share only 60% identity at the amino acid level and strongly differ in substrate specificity and enzyme kinetics. Leukocyte-type 12-LO has the ability to also...
| Keywords: | Alox12, P-12LO, P-12LO, Alox12p, 12S-LOX, 12S-LOX, 12S-lipoxygenase, 12S-lipoxygenase, Lipoxin synthase 12-LO, Lipoxin... |
| Application: | Enzyme activity |
| MW: | 76,4 kD |
489.00€
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(±)10(11)-EpDPA
Item number: Cay10471-100
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA, Cay-90310) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human...
| Keywords: | (±)10,11-EDP, (±)10,11-EpDPE, (±)10,11-epoxy Docosapentaenoic Acid, (±)10,11-epoxy DPA,... |
| Application: | Soluble epoxide hydrolase substrate |
| CAS | 895127-65-8 |
| MW: | 344.5 D |
From 56.00€
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Rabbit Anti-S tag IgG:Biotin
Item number: Cay13471-1
Rabbit anti-S tag IgG conjugated to Biotin Antibody: Rabbit polyclonal anti-S-tag Binding Moiety: Biotin Uses: ELISA, microscropy, and Western blot detection Reactivity: S-tagged proteins Immunogen: KETAAAKFERQHMDS Recommended dilution of 1:500 - 1:10,000. Starting dilution: 1:2,000.Immunogen: KETAAAKFERQHMDS....
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | broad |
488.00€
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CAY10471
Item number: Cay10006735-1
The biological effects of prostaglandin D2 are transduced by at least two 7-transmembrane G-protein coupled receptors, designated DP1 and CRTH2/DP2. BAY-u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of both the TP and CRTH2/DP2...
| Keywords: | TM30089, (+)-3-[[(4-fluorophenyl)sulfonyl]methylamino]-1,2,3,4-tetrahydro-9H-carbazole-9-acetic acid |
| Application: | BAY-u3405 analog |
| CAS | 627865-18-3 |
| MW: | 416.5 D |
From 90.00€
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TGX-221
Item number: Cay10007349-1
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol at the 3 position to produce the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-(3,4)-P2) and PtdIns-(3,4,5)-P3. Class 1 PI3Ks are composed of a p110 catalytic subunit, of which there are 4 isoforms...
| Keywords: | 7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one |
| Application: | PI3K p110beta inhibitor |
| CAS | 663619-89-4 |
| MW: | 364.4 D |
From 43.00€
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PF-543 (hydrochloride)
Item number: Cay17034-5
PF-543 is a potent inhibitor of sphingosine kinase 1 (SPHK1, IC50 = 2 nM) that inhibits sphingosine-1-phosphate (S1P) binding to human recombinant SPHK1 (Ki = 3.6 nM). It is selective for SPHK1 over SPHK2 (IC50 = 356 nM) as well as a panel of protein and lipid kinases and S1P receptors at a concentration of 10 µM....
| Keywords: | 1-[[4-[[3-methyl-5-[(phenylsulfonyl)methyl]phenoxy]methyl]phenyl]methyl]-2R-pyrrolidinemethanol, monohydrochloride |
| Application: | Sphingosine kinase 1 inhibitor |
| CAS | 1706522-79-3 |
| MW: | 502.1 D |
From 43.00€
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UNC0638
Item number: Cay10734-5
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. UNC0638 is...
| Keywords: | 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
| Application: | G9a HMTase inhibitor |
| CAS | 1255580-76-7 |
| MW: | 509.7 D |
From 65.00€
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Glycerophospho-N-Arachidonoyl Ethanolamine
Item number: Cay10011347-1
N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. The different types of NAE can be derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-arachidonoyl ethanolamine is the precursor of arachidonoyl ethanolamide...
| Keywords: | Glycerophospho-Arachidonoyl Ethanolamide, Glycerophosphoanandamide, GP-NArE,... |
| Application: | Bioactive lipid assays |
| CAS | 201738-25-2 |
| MW: | 501.6 D |
From 113.00€
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