6 products were found matching "Cay13708"!
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Anti-Methylated Lysine (biotinylated)
Item number: Cay13728-400
Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of lysine involves methylation. Lysine can be methylated once,...
| Application: | ELISA, ICC/IF, IP, WB |
| Host: | Rabbit |
611.00€
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alpha-Tocotrienol
Item number: Cay10008377-1
alpha-Tocotrienol is an antioxidant and a form of vitamin E that has been found in rice bran and has neuroprotective properties. It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 (Cay-82220), or L-buthionine-(S,R)-sulfoximine (BSO, Cay-14484) in rat striatal cultures when used at...
| Keywords: | 3,4-dihydro-2,5,7,8-tetramethyl-2R-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl)]-2H-1-benzopyran-6-ol |
| Application: | Antioxidant, vitamin E form, neuroprotective agent |
| CAS | 58864-81-6 |
| MW: | 424.7 D |
From 43.00€
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Pyroxamide
Item number: Cay13870-5
Pyroxamide is an inhibitor of histone deacetylases (HDACs), including HDAC1 (IC50 = 0.1-0.2 µM). It induces growth suppression and cell death of certain types of cancer cells in culture.Formal Name: N1-hydroxy-N8-3-pyridinyl-octanediamide. CAS Number: 382180-17-8. Molecular Formula: C13H19N3O3. Formula Weight:...
| Keywords: | N1-hydroxy-N8-3-pyridinyl-octanediamide |
| Application: | Histone deacetylases Inhibitor |
| CAS | 382180-17-8 |
| MW: | 265.3 D |
From 82.00€
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Anti-SET7/9 (FL)
Item number: Cay13780-1
Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly (ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene...
| Keywords: | Anti-SETD7, Anti-SET7/9, Anti-SET7/9, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-H3-K4-HMTase SETD7, Anti-Lysine... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
422.00€
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(E/Z)-4-hydroxy Tamoxifen
Item number: Cay17308-5
(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the...
| Keywords: | 4-hydroxy Tamoxifen, 4-OHT, Afimoxifene, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol |
| Application: | Active tamoxifen metabolite, estrogen receptor agonist/antagonist |
| CAS | 68392-35-8 |
| MW: | 387.5 D |
From 43.00€
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Methimazole
Item number: Cay23718-100
Methimazole is an inhibitor of thyroid hormone synthesis. It is a substrate for thyroid peroxidase that traps oxidized iodide, preventing its use by thyroglobulin for thyroid hormone synthesis. Methimazole (0.4 mg/kg) inhibits the absorption of radiolabeled iodide by the thyroid gland in rats by 80.9%. It reduces...
| Keywords: | NSC 38608, 1,3-dihydro-1-methyl-2H-imidazole-2-thione |
| Application: | Thyroid hormone synthesis inhibitor, Thyroid peroxidase substrate |
| CAS | 60-56-0 |
| MW: | 114.2 D |
From 77.00€
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