8 products were found matching "Cay13707"!

Lipoxin A4-d5 (LXA4-d5) contains five deuterium atoms at the 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of LXA4 by GC- or LC-mass spectrometry (MS). LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or...

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of...

Mepenzolate is an antagonist of muscarinic (M) acetylcholine receptors (Kis = 0.68 and 2.6 nM for human M2 and M3 receptors, respectively). It has antispasmodic activity in the gastrointestinal tract of anesthetized cats and dogs when administered at a dose of 0.5 mg/kg. Mepenzolate decreases airspace enlargement...

Nepafenac-d5 is intended for use as an internal standard for the quantification of nepafenac (Cay-23700) by GC- or LC-MS. Nepafenac is a prodrug form of amfenac, a non-steroidal anti-inflammatory drug (NSAID) and an inhibitor of COX-1 and COX-2. Nepafenac is an inhibitor of prostaglandin (PG) synthase 1 (IC50 = 64.3...

Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind appreciably to any of the other murine EP receptors or DP, TP, FP, or IP receptors. CAY10408...

STF-083010 is an inhibitor of the IRE1/XBP1 pathway, blocking IRE1 endonuclease activity without affecting its kinase activity after endoplasmic reticulum (ER) stress both in vitro and in vivo. STF-083010 (60 µM) reduces the splicing of XBP1 by IRE1 in the presence of thapsigargin (Cay-10522), an ER stress inducer....

AEP-PINACA (Cay-23707) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.Formal Name: (S)-N-(1-amino-1-oxopentan-2-yl)-1-pentyl-1H-indazole-3-carboxamide. Molecular Formula: C18H26N4O2. Formula Weight:...

BPKDi is an inhibitor of protein kinase D (PKD, IC50s = 1, 9, and 1 nM for PKD1, PKD2, and PKD3, respectively). It is selective for PKD over PKCdelta and PKCepsilon, as well as over a panel of additional calcium/calmodulin-dependent protein kinase (CaMK) superfamily members, at 1 µM. It inhibits...