- Search results for Cay13705-100
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14 products were found matching "Cay13705-100"!
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Item number: Cay11705-100
Jasplakinolide is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actin, which is competitive with phalloidin, stabilizes actin filaments in...
Keywords: | NSC 613009,... |
Application: | Actin studies |
CAS | 102396-24-7 |
MW: | 709.7 D |
From 214.00€
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Item number: Cay14705-100
Vildagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4, Ki = 0.003 µM). It is selective for DPP-4 over DPP-2, DPP-8, and DPP-9 (Kis = >500, 0.81, and 0.095 µM, respectively). Vildagliptin (3 mg/kg) decreases plasma glucose levels and increases plasma insulin levels during an oral glucose challenge in Zucker...
Keywords: | 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile |
Application: | DPP4 / DPP8 / DPP9 inhibitor |
CAS | 274901-16-5 |
MW: | 303.4 D |
From 39.00€
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Item number: Cay13570-100
Of the different types of nitric oxide synthases (NOS), the inducible (iNOS) form contributes to inflammation and immune response while the constitutively-expressed endothelial (eNOS) enzyme plays important roles in regulating vascular tone. N-Benzylacetamidine is a potent inhibitor of iNOS (IC50 = 0.20 µM), with...
Keywords: | N-(phenylmethyl)-ethanimidamide, monohydrobromide |
Application: | iNOS inhibitor |
CAS | 186545-76-6 |
MW: | 229.1 D |
From 88.00€
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Item number: Cay37015-100
CD64, also known as high-affinity immunoglobulin gamma receptor I (FcgammaRI), is a transmembrane glycoprotein that binds the Fc region of IgG. It is composed of a ligand-binding alpha-chain, which contains three extracellular Ig-like domains, a transmembrane region, and a cytoplasmic domain, and two gamma-chains,...
Keywords: | Anti-FcRI, Anti-Fcg1, Anti-CD64, Anti-Fcgr1, Anti-Fc-gamma RI, Anti-IgG Fc receptor I, Anti-High affinity immunoglobulin... |
Application: | FC, ICC, IF |
Host: | Rabbit |
From 205.00€
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Item number: Cay10705-100
(±)9-HpODE is a racemic mixture of the fatty acid hydroperoxide product (9(S)-HpODE) formed from lipoxygenase action on linoleic acid. It shows antimicrobial activity against various fungal and bacterial pathogens and thus may play a role in plant defense. In mammalian species, monocyte-induced oxidization of LDL...
Keywords: | (±)9-hydroperoxy-10E,12Z-octadecadienoic acid |
Application: | Bioactive lipid studies |
CAS | 5502-91-0 |
MW: | 312.4 D |
From 134.00€
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Item number: Cay13105-100
Masitinib is an inhibitor of the receptor tyrosine kinase c-Kit (IC50 = 200 nM for the recombinant human enzyme). It is also an inhibitor of PDGFRalpha, PDGFRbeta, and Lyn B (IC50s = 540, 800, and 510 nM, respectively). Masitinib inhibits stem cell factor-induced proliferation of Ba/F3 cells expressing wild-type KIT...
Keywords: | AB-1010, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]-benzamide |
Application: | c-Kit inhibitor |
CAS | 790299-79-5 |
MW: | 498.6 D |
From 92.00€
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Item number: Cay17035-10
TUG-891 is an agonist of free fatty acid receptor 4 (FFAR4/GPR120, EC50s = 0.0436 and 0.0169 µM for the human and mouse receptors, respectively). It is selective for FFAR4 over FFAR1/GPR40 (EC50 = 64.5 µM for the human receptor) and is inactive against FFAR2/GPR43 and FFAR3/GPR41. TUG-891 (1 µM) inhibits...
Keywords: | 4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid |
Application: | GPR120 agonist |
CAS | 1374516-07-0 |
MW: | 364.4 D |
From 46.00€
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Item number: Cay13750-10
16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1. It induces human vascular smooth muscle contractions in vitro. It is 2, 3, and 6 times more potent than PGF2alpha in contracting tracheal, bronchial, and bronchiolar smooth muscle, respectively.Formal Name:...
Keywords: | 16,16-dimethyl PGE1, 9-oxo-11alpha,15R-dihydroxy-16,16-dimethyl-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 41692-15-3 |
MW: | 382.5 D |
From 98.00€
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Item number: Cay13100-100
A common metabolic pathway for several prostaglandins (PGs), including prostaglandin D2 (PGD2), involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the alpha-terminus and oxidation of the...
Keywords: | 9alpha-hydroxy-11,15-dioxo-2,3,4,5-tetranor-prostanoic acid |
Application: | Metabolic studies |
CAS | 1204116-69-7 |
MW: | 298.4 D |
From 141.00€
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Item number: Cay13050-10
Prostaglandin E1 (PGE1) is not a major naturally occurring PG, but is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction, and in neonatal cardiology. COX metabolism of the unusual fatty acid 10,13,16-docosatrienoic acid yields 1a,1b-dihomo...
Keywords: | 1a,1b-dihomo PGE1, 9-oxo-11alpha,15S-dihydroxy-1a,1b-dihomo-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 23452-98-4 |
MW: | 382.5 D |
From 86.00€
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Item number: Cay37005-10
Biotin-H10 is a biotinylated form of the anterior gradient 2 (AGR2) binding peptide H10. It has been used in ELISA and co-immunoprecipitation assays to assess AGR2 levels in cancer cells.Formal Name:...
Keywords: | Biotin-GGGSGMKMQVRIYLV-OH, Biotin-Gly-Gly-Gly-Ser-Gly-Met-Lys-Met-Gln-Val-Arg-Ile-Tyr-Leu-Val-OH,... |
Application: | AGR2 binding peptide H10, biotinylated form |
MW: | 1822.2 D |
From 76.00€
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Item number: Cay13005-100
4-Pyridylamide oxime is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: N-hydroxy-4-pyridinecarboximidamide. CAS Number: 1594-57-6. Synonyms: NSC 43969. Molecular Formula: C6H7N3O. Formula Weight: 137.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid....
Keywords: | NSC 43969, N-hydroxy-4-pyridinecarboximidamide |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 1594-57-6 |
MW: | 137.1 D |
From 22.00€
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