ART NR.: Pro-30233 (100 µl)
Anwendungen: WB, IHC, ELISA
Immunogen: Purified recombinant fragment of human GRIA3 expressed in E. coli.
UniProt ID: P42263
Suche mit UniProt ID
Geninformationen: GeneID 2892
Schlagworte: Anti-GluA3, Anti-GRIA3, Anti-GLUR3, Anti-GluR-3, Anti-GluR-C, Anti-GluR-K3, Anti-Glutamate receptor 3, Anti-AMPA-selective glutamate receptor 3, Anti-Glutamate receptor ionotropic, AMPA 3
Ascitic fluid containing 0.03% sodium azide. Protein function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. [The UniProt Consortium]