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AZD 8835
AZD 8835

Item number: Cay29166-10

AZD 8835 is an inhibitor of PI3Kalpha and PI3Kdelta (IC50s = 6.2 and 5.7 nM, respectively). It is selective for PI3Kalpha and PI3Kdelta over PI3Kbeta and PI3Kgamma (IC50s = 431 and 90 nM, respectively). AZD 8835 inhibits Akt phosphorylation in PIK3CA constitutively active mutant BT474 cells and Jeko-1 B cells that...
Keywords: 1-[4-[5-[5-amino-6-[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]-2-pyrazinyl]-1-ethyl-1H-1,2,4-triazol-3-yl]-1-piperidinyl]...
Application: PI3Kalpha / PI3Kdelta inhibitor
CAS 1620576-64-8
MW: 469.5 D
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