5 products were found matching "Cay13739-1"!
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M2N12
Item number: Cay37391-1
M2N12 is a clickable inhibitor of cell division cycle 25 (Cdc25, IC50s = 0.53, 1.39, and 0.09 µM for Cdc25A, Cdc25B, and Cdc25C, respectively). It is composed of a naphthoquinone derivative functionalized with a clickable cyclic azide group. M2N12 inhibits the proliferation of A549 lung cancer and MDA-MB-231 and...
| Keywords: | 6-chloro-7-[[[1-[(4-methylphenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]amino]-5,8-quinolinedione |
| Application: | Clickable Cdc25 inhibitor, click chemistry |
| CAS | 2376577-06-7 |
| MW: | 393.8 D |
From 110.00€
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Anti-SET7/9
Item number: Cay13731-1
Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene...
| Keywords: | Anti-SETD7, Anti-SET7/9, EC=2.1.1.43, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-SET... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
432.00€
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Anti-TRF2
Item number: Cay13791-1
Telomeric repeat binding factor (TRF2) is a ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect...
| Keywords: | Telomeric Repeat Binding Factor 2, TERF2, TRBF2, TTAGGG Repeat Binding Factor 2 |
| Application: | ChIP, ICC, IF, IHC, IP, WB |
| Host: | Goat |
| Species reactivity: | human |
417.00€
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SAR260301
Item number: Cay17391-1
SAR260301 is an inhibitor of phosphatidylinositol 3-kinase (PI3K) isoform beta (IC50 = 52 nM). It is selective for p110beta over other PI3K isoforms. SAR260301 demonstrates significant in vivo activity in a UACC-62 xenograft model in mice. It has synergistic antitumor activity when combined with the BRAF inhibitor...
| Keywords: | 2-[2-[(2S)-2,3-dihydro-2-methyl-1H-indol-1-yl]-2-oxoethyl]-6-(4-morpholinyl)-4(3H)-pyrimidinone |
| Application: | PI3K beta inhibitor |
| CAS | 1260612-13-2 |
| MW: | 354.4 D |
From 52.00€
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Goat Anti-Chicken IgY:SureLight(R) APC
Item number: Cay13391-1
Goat Anti-Chicken IgY conjugated to SureLight(R) APC, 100µg Antibody: Goat polyclonal Anti-chicken IgY Excitation max. lambda: 650 nm Emission max. lambda: 660 nm Uses: Flow cytometry/Fluorescence-activated cell sortingEmission: 660 nm. Excitation: 650 nm. Formulation: (Request formulation change), A lyophilized...
| Application: | IF |
| Host: | Goat |
| Species reactivity: | chicken |
293.00€
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