Anti-Fatty Acid Amide Hydrolase

Anti-Fatty Acid Amide Hydrolase
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay101600-1 1 each -

6 - 10 business days*

422.00€
 
Fatty acid amide hydrolase (FAAH) is a serine hydrolase with a major role in the hydrolysis of... more
Product information "Anti-Fatty Acid Amide Hydrolase"
Fatty acid amide hydrolase (FAAH) is a serine hydrolase with a major role in the hydrolysis of endocannabinoids. It is composed of an N-terminal transmembrane domain, a catalytic domain containing an amidase signature sequence, a polyproline sequence, and a monotopic membrane binding domain. FAAH is localized to microsomal and mitochondrial membranes and is highly expressed in the CNS but can also be found in peripheral tissues such as lung, gastrointestinal tract, kidney, liver, bladder, prostate, and testis. It primarily catalyzes the inactivation of the endogenous endocannabinoid arachidonoyl ethanolamide (AEA, Cay-90050) via hydrolysis to arachidonic acid and ethanolamine but has broad substrate selectivity towards fatty acid amides, including oleamide, N-acyltaurines, and other N-acylethanolamines. Genetic or pharmacologic knockdown of FAAH increases levels of AEA and dampens pain sensitivities and inflammatory endpoints in rodent models of inflammatory pain, allergic contact dermatitis, inflammatory bowel disease, and neuropathic pain. Cayman's Fatty Acid Amide Hydrolase Polyclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications.Synonyms: Anandamide Amidohydrolase 1, FAAH, Oleamide Hydrolase 1, PSAB. Immunogen: Synthetic peptide from the C-terminal region of rat FAAH. Formulation: (Request formulation change), 500 µl peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: IHC and WB. UniProt Accession #: P97612. Origin: Animal/Rabbit.
Keywords: Anti-Faah, Anti-Faah1, Anti-Anandamide amidase, Anti-Anandamide amidase, Anti-Oleamide hydrolase 1, Anti-Oleamide hydrolase 1, Anti-Fatty acid ester hydrolase, Anti-Fatty acid ester hydrolase, Anti-Anandamide amidohydrolase 1, Anti-Anandamide amidohydrola
Supplier: Cayman Chemical
Supplier-Nr: 101600

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse, ferret
Immunogen: Synthetic peptide from the C-terminal region of rat FAAH
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-Fatty Acid Amide Hydrolase"
Write a review
or to review a product.
Viewed