Anti-EZH2, NT (KMT6) (Azide free) (HRP)

Anti-EZH2, NT (KMT6) (Azide free) (HRP)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
035290-HRP.200 200 µl - -

3 - 19 business days*

993.00€
 
EZH2, SUZ12, and EED form a complex that methylates nucleosomal histone H3 at Lys27. EZH2... more
Product information "Anti-EZH2, NT (KMT6) (Azide free) (HRP)"
EZH2, SUZ12, and EED form a complex that methylates nucleosomal histone H3 at Lys27. EZH2 contains a SET domain, a signature motif for all known histone lysine methyltransferases except the H3-K79 methyltransferase DOT1, and is therefore likely to be the catalytic subunit. Consequently, EZH2 is thought to regulate gene expression by controlling chromatin structure. Several lines of evidence suggested a critical role for the EZH2 protein during normal and perturbed development of the hematopoietic and central nervous systems. The EZH2 protein has been shown to associate with the VAV1 protooncoprotein and with the XNP protein, the product of a gene associated with mental retardation. Additionally, due to mapping of EZH2 to the 7q35-q36 chromosomal region associated with myeloid disorders, this protein is suggested to participate in the genetic events triggering myeloid leukemia. Applications: Suitable for use in Western Blot, Immunohistochemistry, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:50-100, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-EZH2, Anti-KMT6, Anti-ENX-1, EC=2.1.1.43, Anti-Enhancer of zeste homolog 2, Anti-Lysine N-methyltransferase 6, Anti-Histone-lysine N-methyltransferase EZH2
Supplier: United States Biological
Supplier-Nr: 035290-HRP

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Species reactivity: human
Immunogen: EZH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EZH2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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