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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E9085-02C.100 | 100 µg | - | - |
3 - 19 business days* |
1,022.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
EZH2 (enhancer of zeste homolog 2), also known as Enx1, is a member of the polycomb group of... more
Product information "Anti-EZH2 (Histone-lysine N-methyltransferase EZH2, Enhancer of zeste homolog 2, ENX-1, Lysine N-met"
EZH2 (enhancer of zeste homolog 2), also known as Enx1, is a member of the polycomb group of proteins and is involved in cell cycle regulation. EZH2 represses transcription via trimethylation of histone H3 on Lys27 (H3K27) as indicated by the fact that RNAi-mediated knockdown of EZH2 resulted in a loss of H3K27 trimethylation. EZH2 is ubiquitously expressed during early embryo genesis, and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. In the adult, EZH2 is restricted to the spleen, testis and placenta. EZH2 and BMI-1 genes are coexpressed in Reed-Sternberg cells of Hodgkin's disease. Coexpression of BMI-1 and EZH2 is also associated with cycling cells and degree of malignancy in B-cell non-Hogkin's lymphoma. EZH2 is involved in the progression of prostate cancer, and has been identified as a marker of aggressive breast cancer. Two transcript variants encoding distinct isoforms have been identified for this gene. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:5000, Optimal dilutions to be determined by the researcher. Positive Control: HeLa Nuclear Extracts, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-KMT6, EC=2.1.1.43 |
Supplier: | United States Biological |
Supplier-Nr: | E9085-02C |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 9H236 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Recombinant fusion protein of aa1-286 of human EZH2 tagged with MBP. Cellular Localization: Nucleus. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K11430 | Matching products |
UniProt ID : | Q15910 | Matching products |
Gene ID | GeneID 2146 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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