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Anti-EBI-3

ART NR.: 209-401-B66 (100 µg)

Hersteller: Rockland

Datenblatt

Anwendungen: ELISA, WB

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: mature length recombinant human EBI3 protein produced in E.coli

UniProt ID: Q14213
Suche mit UniProt ID

Geninformationen: GeneID 10148

Schlagworte: Anti-EBI3, Anti-IL27B, Anti-IL-27B, Anti-IL-27 subunit beta, Anti-EBV-induced gene 3 protein, Anti-Interleukin-27 subunit beta, Anti-Epstein-Barr virus-induced gene 3 protein

100 µg

371 €

333 €

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Bemerkungen: Protein function: Cytokine with pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon- gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. [The UniProt Consortium]

Die Preise verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.





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