2 products were found matching "Cay100029-500"!
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SMI-4a
Item number: Cay11029-50
The serine/threonine Pim kinases have been suggested to promote the activity of the rapamycin-sensitive mammalian target of rapamycin (mTORC1), which regulates cell growth and survival. Pim kinases are overexpressed in solid cancers and hematologic malignancies, and as such have become targets of small molecule...
| Keywords: | 5Z-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione |
| Application: | Pim-1/Pim-2 kinase inhibitor |
| CAS | 438190-29-5 |
| MW: | 273.2 D |
From 60.00€
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MK-571
Item number: Cay10029-50
MK-571 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes). It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTE4 (Cay-20410) in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1,...
| Keywords: | L-660,711, (E)-3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic... |
| Application: | CysLT1 receptor antagonist |
| CAS | 115104-28-4 |
| MW: | 515.1 D |
From 43.00€
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