Anti-CB1 Receptor

The CB1 receptor and the splice variant CB1a are localized mainly in the brain. The CB1 receptor is a G-protein coupled receptor that binds the active component of cannabis, Delta9-tetrahydrocannabinol. Human and rat CB1 receptors exhibit 97.3% homology at the amino acid level over the complete protein, and 100% homology within the peptide sequence used to make this antibody. This peptide exhibits no homology with the CB2 receptor. Based on the amino acid sequence, the CB1 receptor has a molecular weight of approximately 52,800. The CB1 receptor and the splice variant CB1a are localized mainly in the brain, whereas the CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells. Cayman's CB1 Receptor Polyclonal Antibody can be used for Western blot and immunohistochemistry applications. The antibody recognizes the N-terminal extracellular region of the CB1 receptor at 40 kDa from human samples.Synonyms: Cannabinoid Receptor 1, CNR1. Immunogen: Synthetic peptide from the N-terminal extracellular region of human CB1 receptor. Formulation: (Request formulation change), 500 µl of peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: WB and IHC. UniProt Accession #: P21554. Origin: Animal/Rabbit.