Anti-Bcl-2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-675A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-675A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent... more

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Product information "Anti-Bcl-2"

Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785). [The UniProt Consortium]

Keywords:	Anti-BCL2, Anti-Apoptosis regulator Bcl-2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-675A

Properties

Application:	WB, IP, IHC, FC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rhesus monkey, chimpanzee, northern white-cheeked gibbon)
Immunogen:	Synthetic peptide. The epitope recognized by A303-675A maps to a region between residue 50 and 100 of human B-cell CLL/lymphoma 2 using the numbering given in entry NP_000624.2 (GeneID 596).
Format:	Antigen Affinity Purified