19 products were found matching "Cay11610"!

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Anti-Amyloid-beta   (Clone 6C3, MOAB-2)
Anti-Amyloid-beta (Clone 6C3, MOAB-2)

Item number: Cay11610-200

Amyloid plaques composed primarily of the 42 amino acid form of amyloid-beta peptide (Abeta42) are a hallmark of Alzheimer's disease (AD). However, the roles of the various amyloid beta peptide(s), especially Abeta42, related to the neurotoxicity characteristic of AD remains unclear. A major hindrance to evaluating...
Keywords: Anti-A4, Anti-C99, Anti-C83, Anti-C80, Anti-C31, Anti-ABPP, Anti-APPI, Anti-CVAP, Anti-PreA4, Anti-PN-II, Anti-N-APP,...
Application: ELISA, ICC, IP, WB
Host: Mouse
Species reactivity: human
456.00€ *
Review
Decitabine
Decitabine

Item number: Cay11166-10

5-Azacytidine is an analog of cytidine which can be incorporated into DNA, inhibit DNA methyltransferases, and cause hypomethylation of cytosine residues in the absence of any significant mutagenic effects. Decitabine is a 2'-deoxy analog of 5-azacytidine which similarly causes hypomethylation of DNA by inhibiting...
Keywords: 5-aza-2'-Deoxycytidine, DAC, NSC 127716, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one
Application: Cytidine analog
CAS 2353-33-5
MW: 228.2 D
From 64.00€ *
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4-methoxy-N,N-Dimethylcathinone (hydrochloride)
4-methoxy-N,N-Dimethylcathinone (hydrochloride)

Item number: Cay11666-10

Methedrone (4-methoxymethcathinone) is a substituted cathinone with psychoactive actions. Its use as a recreational drug and its toxicity have recently been reported. 4-methyl-N,N-DMC is an analog of methedrone, differing by the presence of a second aminomethyl group. Its biological and toxicological properties have...
Keywords: 4-methyl-N,N-DMC, N-Methylmethedrone, 2-(dimethylamino)-1-(4-methoxyphenyl)-1-propanone, monohydrochloride
Application: Analytical reference standard, Psychoactive substituted cathinone
CAS 1089307-23-2
MW: 243.7 D
From 266.00€ *
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Monocrotaline
Monocrotaline

Item number: Cay16666-100

Monocrotaline is a natural 11-membered macrocyclic pyrrolizidine alkaloid used in an animal model of pulmonary hypertension. It is metabolized by cytochrome P450 3A4 in the liver to monocrotaline pyrrole. Administration of monocrotaline or its metabolite monocrotaline pyrrole to rats causes progressive lung injury...
Keywords: Crotaline, MCT, NSC 28693,...
Application: Pulmonary hypertension inducer
CAS 315-22-0
MW: 325.4 D
From 84.00€ *
Review
trans-3'-Hydroxycotinine
trans-3'-Hydroxycotinine

Item number: Cay16100-1

trans-3'-Hydroxycotinine (3HC) is a product of CYP2A6 metabolism of the primary nicotine metabolite, cotinine (Cay-15314). Cotinine has a longer metabolic half-life compared to 3HC (16 hours vs. 5 hours). The ratio of 3HC to cotinine, termed the nicotine metabolite ratio, correlates with nicotine clearance from the...
Keywords: 3HC, 3R-hydroxy-1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone
Application: Nicotine metabolite, CYP2A6 activity biomarker
CAS 34834-67-8
MW: 192.2 D
From 77.00€ *
Review
Prostaglandin F2alpha 1,11-lactone
Prostaglandin F2alpha 1,11-lactone

Item number: Cay16110-5

Prostaglandin F2alpha (PGF2alpha) 1,11-lactone is a lipid-soluble internal ester of PGF2alpha. Hydrolysis of the lactone by plasma esterases readily produces free PGF2alpha in rats and monkeys, but not in humans. PGF2alpha 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity compared to...
Keywords: PGF2alpha 1,11-lactone, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1,11-lactone
Application: Bioactive lipid assays
CAS 62410-84-8
MW: 336.5 D
From 117.00€ *
Review
Anti-HA IgG:SureLight(R) APC [Mouse]
Anti-HA IgG:SureLight(R) APC [Mouse]

Item number: Cay16610-100

Mouse Anti-HA IgG conjugated to SureLight(TM) APC, 100ug Antibody: Mouse monoclonal Anti-HA (Hemagglutinin) IgG1 Clone: 16B12 Uses: Flow cytometry, cell-based assays, microarrays and microplate applications Spectral Characteristics: Visible absorption maximum = 652 nm Emission maximum = 657.5 nm This monoclonal...
Application: FC, Cell-based assays, Microarray / microplate applications
Host: Mouse
Species reactivity: broad
675.00€ *
Review
Pellitorine
Pellitorine

Item number: Cay11662-10

Pellitorine is an amide alkaloid that has been found in P. nigrum and has diverse biological activities. Pellitorine is cytotoxic to HL-60 leukemia and MCF-7 breast cancer cells (IC50s = 13 and 1.8 µg/ml, respectively). It inhibits production of TNF-alpha, IL-1alpha, and IL-1beta and phosphorylation of ERK1/2...
Keywords: (2E,4E)-N-(2-methylpropyl)-2,4-decadienamide
Application: ACAT inhibitor
CAS 18836-52-7
MW: 223.4 D
From 37.00€ *
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A-796260
A-796260

Item number: Cay11606-10

A-796260 is a synthetic cannabinoid (CB) that shows high selectivity for the CB2 receptor (Ki = 0.77 nM) over the CB1 receptor (Ki = 2,100 nM). It also shows efficacy in vivo in models of inflammatory, post-operative, neuropathic, and osteoarthritic pain, activities which are selectively blocked by CB2...
Keywords: LTI-258, [1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone
Application: Analytical reference standard, Synthetic cannabinoid (high CB2 receptor selectivity)
CAS 895155-26-7
MW: 354.5 D
From 291.00€ *
Review
XLR11 N-(4-pentenyl) analog
XLR11 N-(4-pentenyl) analog

Item number: Cay11688-10

XLR11 (Cay-11565) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor. XLR11 also has an N-(5-fluoropentyl) chain, which increases binding to both CB receptors. XLR11 N-(4-pentenyl) analog is a...
Keywords: UR-144 N-(4-pentenyl) analog, (1-(pent-4-en-1-yl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
Application: Analytical reference standard, Synthetic cannabinoid analog
CAS 1445578-20-0
MW: 309.5 D
From 291.00€ *
Review
2-Fluoroisocathinone (hydrochloride)
2-Fluoroisocathinone (hydrochloride)

Item number: Cay11607-10

2-Fluoroisocathinone is a compound that structurally mimics substituted cathinones and phenethylamines and has been listed as a controlled substance in the United States. The physiological and toxicological properties of this compound have not been reported. This compound is intended for research and forensic...
Keywords: 2-FIC, 1-amino-1-(2-fluorophenyl)-2-propanone, monohydrochloride
Application: Analytical reference standard, Structurally mimics substituted cathinones/phenethylamines
CAS 1909305-71-0
MW: 203.6 D
From 84.00€ *
Review
GDC-0941
GDC-0941

Item number: Cay11600-10

The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110alpha, beta, delta, and gamma with IC50 values of 3, 33, 3, and 75 nM, respectively. It is much less...
Keywords: GNE-0941, Pictilisib, Pictrelisib,...
Application: PI3K inhibitor
CAS 957054-30-7
MW: 513.6 D
From 180.00€ *
Review
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