- Search results for A1382.1
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4 products were found matching "A1382.1"!
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Item number: 374162.100
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of...
Keywords: | EXP, MBNL1, Muscleblind-like protein 1, Triplet-expansion RNA-binding protein |
MW: | 57 |
From 511.00€
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Item number: 374816.100
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the...
Keywords: | PPM1A, PPPM1A, PP2C-alpha, EC=3.1.3.16, Protein phosphatase IA, Protein phosphatase 1A, Protein phosphatase 2C isoform alpha |
MW: | 69,3 |
From 511.00€
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Item number: ARG41382.100
Protein function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle...
Keywords: | Anti-MEF2, Anti-MEF2A, Anti-Myocyte-specific enhancer factor 2A, Anti-Serum response factor-like protein 1 |
Application: | FC, ICC, IF, IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
624.00€
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Item number: A1355-82.100
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, also known ALKBH2, belongs to the ALKB family. Expressed in heart, colon, liver, testis, ovary, prostate and small intestine, ALKBH2 uses iron as a cofactor and functions as a dioxygenase that catalyzes the repair of alkylated DNA and RNA containing...
Keywords: | EC=1.14.11.-, Alkylated DNA repair protein alkB homolog 2, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 |
MW: | 31,4 kD |
From 568.00€
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