Anti-ATF6

Anti-ATF6
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-720A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A303-720A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Transmembrane glycoprotein of the endoplasmic reticulum that functions as a... more
Product information "Anti-ATF6"
Protein function: Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'- ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina. [The UniProt Consortium]
Keywords: Anti-ATF6
Supplier: Bethyl Laboratories
Supplier-Nr: A303-720A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: rabbit, gorilla, chimpanzee, african elephant, naked mole rat, northern white-cheeked gibbon)
Immunogen: Synthetic peptide. The epitope recognized by A303-720A maps to a region between residue 620 and 670 of human Activating Transcription Factor 6 using the numbering given in entry NP_031374.2 (GeneID 22926).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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