103 products were found matching "A2275-86S"!

Anti-human APP770 was raised using a synthetic 15-aa peptide near the extracellular, KPI-region (301-316 aa) of human APP770 (1). Peptide was conjugated to KLH. Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. One of the most important...

Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. One of the most important and initial step involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43aa peptides (beta amyloid1-40, 1-42,...

Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. In disease state oligomerization, extensive amyloid oligomerization creates plaques in neural tissue that...

Sequence (linear): Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val, Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see...

Fusion Partners: Spleen cells from immunized BALB/c mice were fused with cells of the mouse NSO/1 myeloma cell line. Recommended Negative Controls: Mouse IgG1 Negative Control: RPE , Applications:, Flow Cytometry: Neat, Optimal working dilutions to be determined by researcher., , Flow Cytometry: Use 10ul of the...

A naturally occurring neurotoxin produced by hoplonemertine sea worms competes with the natural neurotransmitter acetylcholine when binding to nicotinic receptor sites. , Solubility: Chloroform , Storage and Stability:, May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum...

Solubility: , Chloroform, Method for Determining Identity: Proton NMR Spectroscopic Analysis and Mass Spectrometric analysis, TLC Conditions: SiO2: Dichloromethane: Methanol: Ammonium Hydroxide, 8ml, 2ml: 5 drops, Visualized with UV, Single spot, Rf=0.5, Storage and Stability: May be stored at RT for short-term...

Amyloid A, Serum, Human (Serum, Amyloid A, SAA) BioAssay(TM) ELISA Kit is to be used for the in vitro quantitative determination human serum amyloid A (SAA) concentrations in serum, plasma, cell culture supernatant and other biological fluids. Amyloidosis includes a family of diseases which have in common the...

Amyloid Precursor Protein (APP) is an integral membrane protein with a large ectodomain, a transmembrane domain, and a short cytoplasmic tail. APP is proteolytically cleaved by b-secretase (BACE) to generate the APP N-terminal fragment (sbAPP) with Mr100kD and a C-terminal fragment (C99) with Mr12kD. The smaller...

Sequence: , GYENPTYKFFEQMQN , Location: Amino acids 737-751 of human APP (1) , Applications: The peptide is used for blocking the activity of anti-APP. Incubating the peptide with equal volume of antibody for 30 min at 37¡C usually completely blocks the antibody activity in Western blotting. Storage and Stability:...

Sequence: , DAEFRHDSGY , Location: Amino acids 653 to 662 of human APP (1) , Applications: The peptide is used for blocking the activity of anti-APP. Incubating the peptide with equal volume of antibody for 30 min at 37¡C usually completely blocks the antibody activity in Western blotting. Storage and Stability:...

Amyloid-beta precursor protein (APP) is the source of the amyloid-beta (Ab) peptide found in neuritic plaques of Alzheimer's disease (AD) patients. APP is aglycosylated transmembrane protein with a long extracellular N-terminal domain, a short intracellular C-terminal domain, and an Abeta-segment of intermediate...