5 products were found matching "139284"!
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244cis
Item number: Cay39284-10
244cis is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing 244cis and encapsulating an mRNA reporter specifically accumulate in the lungs and induce lower serum chemokine (C-C motif) ligand 2 (CCL2) levels than LNPs containing SM-102 (Cay-33474) in mice....
| Keywords: | di((Z)-non-2-en-1-yl) 9,9'-((2-(4-(9-(((Z)-non-2-en-1-yl)oxy)-9-oxononyl)piperazin-1-yl)ethyl)azanediyl)dinonanoate |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 970.6 D |
From 122.00€
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BPTES
Item number: Cay19284-5
BPTES is an allosteric inhibitor of kidney-type glutaminase 1 (GLS1, IC50 = 3.3 µM) that drives the formation of inactive GLS1 tetramers. It is selective for GLS1 over GLS2, glutamate dehydrogenase, and gamma-glutamyl transpeptidase. BPTES decreases glutaminase activity and reduces proliferation of aerobic P493...
| Keywords: | N,N'-[thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bis-benzeneacetamide |
| Application: | GLS inhibitor |
| CAS | 314045-39-1 |
| MW: | 524.7 D |
From 43.00€
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MS-275
Item number: Cay13284-1
MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 µM). However, it does not inhibit HDAC8 (IC50 > 100 µM). MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell growth, differentiation, and tumor development in...
| Keywords: | Entinostat, SNDX 275, N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-carbamic acid, 3-pyridinylmethyl ester |
| Application: | HDAC inhibitor |
| CAS | 209783-80-2 |
| MW: | 376.4 D |
From 28.00€
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Anti-GREB1
Item number: E-AB-13284.200
This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Protein...
| Keywords: | Anti-GREB1, Anti-KIAA0575, Anti-Protein GREB1, Anti-Gene regulated in breast cancer 1 protein, GREB1 Polyclonal Antibody |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 71.00€
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Anti-RAP1B
Item number: E-AB-13928.60
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This...
| Keywords: | Anti-RAP1B, Anti-Ras-related protein Rap-1b, Anti-GTP-binding protein smg p21B, RAP1B Polyclonal Antibody |
| Application: | WB, IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 71.00€
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