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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
044504.10 | 10 µg | - | - |
3 - 19 business days* |
454.00€
|
||
044504.30 | 30 µg | - | - |
3 - 19 business days* |
796.00€
|
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind... more
Product information "Angiopoietin-2, Recombinant, Human (Ang-2, Ang2, Angpt2)"
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. Sequence: Human angiopoietin-2 (aa19-496) is fused at the N-terminus to a FLAG(R)-tag, expressed in HEK 293 cells. Binds to the human and mouse Tie-2 receptor. Molecular Weight: ~70kD (SDS-PAGE), Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | ANG-2, ANGPT2, Angiopoietin-2 |
Supplier: | United States Biological |
Supplier-Nr: | 044504 |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
Format: | Highly Purified |
Database Information
KEGG ID : | K05466 | Matching products |
UniProt ID : | O15123 | Matching products |
Gene ID | GeneID 285 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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