Angiopoietin-2, Recombinant, Human (Ang-2, Ang2, Angpt2)

Angiopoietin-2, Recombinant, Human (Ang-2, Ang2, Angpt2)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
044504.10 10 µg - -

3 - 19 business days*

454.00€
044504.30 30 µg - -

3 - 19 business days*

796.00€
 
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind... more
Product information "Angiopoietin-2, Recombinant, Human (Ang-2, Ang2, Angpt2)"
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. Sequence: Human angiopoietin-2 (aa19-496) is fused at the N-terminus to a FLAG(R)-tag, expressed in HEK 293 cells. Binds to the human and mouse Tie-2 receptor. Molecular Weight: ~70kD (SDS-PAGE), Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: ANG-2, ANGPT2, Angiopoietin-2
Supplier: United States Biological
Supplier-Nr: 044504

Properties

Application: Bioassays
Conjugate: No
Host: Human cells
Species reactivity: human
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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