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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABD-13504 | 100 tests | - |
3 - 8 business days* |
487.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Caspases play important roles in apoptosis and cell signaling. The activation of caspase-3... more
Product information "Amplite(TM) Fluorimetric Caspase 3/7 Assay Kit (Red Fluorescence)"
Caspases play important roles in apoptosis and cell signaling. The activation of caspase-3 (CPP32/apopain) is important for the initiation of apoptosis. Caspase 3 is also identified as a drug-screening target. Caspase 3 has substrate selectivity for the peptide sequence Asp-Glu-Val-Asp (DEVD). This Amplite(TM) Caspase-3 Assay Kit uses Z-DEVD-ProRed(TM) as the fluorogenic indicator for assaying caspase-3 activity. Cleavage of R110 peptides by caspases generates strongly red fluorescent ProRed(TM) that can be monitored fluorimetrically at about 620 nm with excitation of about 530 nm. Z-DEVD-ProRed(TM) is recognized as the most sensitive red fluorogenic caspase 3/7 substrate. This kit can be used to continuously measure the activities of caspase-3 in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer. It can also be used with flow cytometry for analyzing cell apoptosis and the activities of caspases 3 and 7.
Supplier: | AAT Bioquest |
Supplier-Nr: | 13504 |
Properties
Application: | Caspase-3 assays |
Format: | Homog. |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Signal Word: | Warning |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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