8 products were found matching "Cay15881"!

No results were found for the filter!
Amitriptyline (hydrochloride)
Amitriptyline (hydrochloride)

Item number: Cay15881-5

Amitriptyline is a first generation tricyclic antidepressant. It inhibits serotonin (5-HT) uptake by isolated human platelets by 39 and 68% when used at concentrations of 1 and 4 µg/ml, respectively, and inhibits norepinephrine uptake in rat brain by 77% when administered at a dose of 10 mg/kg. It is also an...
Keywords: NIH 10794, Ro 4-1575, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, monohydrochloride
Application: Serotonin / noradrenalin transporter inhibitor
CAS 549-18-8
MW: 313.9 D
From 43.00€ *
Review
Ramipril
Ramipril

Item number: Cay15558-1

Ramipril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor ramiprilat (Cay-15557). Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats. It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis....
Keywords: HOE 498,...
Application: Angiotensin-converting enzyme (ACE) inhibitor
CAS 87333-19-5
MW: 416.5 D
From 84.00€ *
Review
Ganglioside GT1b (bovine) (sodium salt)
Ganglioside GT1b (bovine) (sodium salt)

Item number: Cay15588-1

Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 µM, respectively. Ganglioside GT1b-containing...
Keywords: Ganglioside G1 Mixture
Application: Trisialoganglioside
MW: 2126.3 D
From 145.00€ *
Review
AZD 8330
AZD 8330

Item number: Cay11588-1

AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells. AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.Formal Name:...
Keywords: ARRY-424704, 2-[(2-fluoro-4-iodophenyl)amino]-1,6-dihydro-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-3-pyridinecarboxamide
Application: MEK inhibitor
CAS 869357-68-6
MW: 461.2 D
From 84.00€ *
Review
Doxepin (hydrochloride)
Doxepin (hydrochloride)

Item number: Cay15888-1

Doxepin is a tricyclic antidepressant that binds to the serotonin (5-HT) transporter (SERT) and norepinephrine transporter (NET, Kds = 68 and 29.5 nM, respectively). It is a histamine H1 receptor antagonist (Ki = 1.23 nM). Doxepin selectively binds to SERT and NET over the dopamine transporter (DAT, Kd = 12,100 nM)...
Keywords: 3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine, monohydrochloride
Application: Histamine, serotonin, adrenergic, muscarinic receptor antagonist, Norepinephrine reuptake inhibitor
CAS 1229-29-4
MW: 315.8 D
From 50.00€ *
Review
Dexmedetomidine (hydrochloride)
Dexmedetomidine (hydrochloride)

Item number: Cay15581-5

Dexmedetomidine is the (S)-enantiomer of medetomidine, an imidazole compound that binds to alpha2-adrenoceptors (Ki = 1.08 nM) with high affinity and selectivity compared to that of alpha1-adrenoceptors (Ki = 1.8 µM). Dexmedetomidine produces analgesic, sedative, and anxiolytic effects through both presynaptic...
Keywords: Dex, Precedex, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride
Application: alpha2-adrenergic receptor agonist
CAS 145108-58-3
MW: 236.7 D
From 66.00€ *
Review
5'-Ethynyl-2'-deoxycytidine
5'-Ethynyl-2'-deoxycytidine

Item number: Cay11581-25

5'-Ethynyl-2'-deoxycytidine (EdC) is a nucleoside analog that inhibits replication of the herpes simplex virus-1 (HSV-1) KOS strain (ID50 = 0.2 µg/mL). It also reduces virus-induced cytopathogenicity of HSV-1, HSV-2, and vaccinia virus strains in PRK cells (MICs = 0.2-0.4, 1-2, and 5 µg/ml, respectively). EdC is an...
Keywords: 2'-deoxy-5-Ethynylcytidine, EdC, 2'-deoxy-5-ethynyl-cytidine
CAS 69075-47-4
MW: 251.2 D
From 43.00€ *
Review
Clomipramine (hydrochloride)
Clomipramine (hydrochloride)

Item number: Cay15884-1

Clomipramine is a tricyclic antidepressant, the 3-chlorinated derivative of imipramine (Cay-15890). Like imipramine, clomipramine potently inhibits serotonin and norepinephrine reuptake (Kis = 7.4 and 96 nM, respectively). It also is an antagonist at histamine, muscarinic acetylcholine, alpha1-adrenergic, and...
Keywords: 3-chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine, monohydrochloride
Application: Serotonin norepinephrine reuptake inhibitor
CAS 17321-77-6
MW: 351.3 D
50.00€ *
Review