10 products were found matching "Cay15986-50"!

Dutasteride is a dual inhibitor of 5alpha-reductase types I and II (Kis = 6 and 7 nM, respectively). Its inhibition is time-dependent inhibitor with apparent Ki values of 17 and 4.3 nM at 10- and 30-minute reaction times, respectively. Dutasteride decreases prostate weight in a rat model of benign prostatic...

Adefovir is an active metabolite of the antiviral nucleoside analog adefovir dipivoxil (Cay-28373). Adefovir is formed from adefovir dipivoxil by gastrointestinal carboxylesterase 2 (CES2). It inhibits cytopathogenicity induced by herpes simplex virus 1 (HSV-1) and HSV-2 (EC50 = 7 µg/ml for both in E6SM cells),...

Vitamin K is a dietary nutrient essential for the normal biosynthesis of factors that are required for blood clotting. It has also been shown to inhibit cell growth. Vitamin K3 is a synthetic form of vitamin K that acts as a precursor to vitamin K2. It is capable of both redox cycling and arylating nucleophilic...

7-ethoxy-4-Methylcoumarin is a fluorophore that has been used to monitor functional activity of cytochrome P450 (CYP)1A1, CYP2B4, and CYP2B6. It demonstrates excitation/emission maxima of 318 and 377 nm, respectively in methanol and 360 and 449 nm, respectively in dealkylase.Formal Name:...

WB 1:500 - 1:2000. Protein function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription. [The UniProt Consortium]

4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid (Cay-18263) in many non-mammalian organisms, including bacteria and fungi. Folates, like tetrahydrofolic acid, have critical roles in the metabolism of nucleic acid precursors and several amino acids, as well as...

Metolazone is a thiazide-like diuretic. It inhibits the Na+/Cl- cotransporter (IC50 = 0.3 µM for the rat transporter) and human carbonic anhydrase VII (CAVII), CAXII, and CAXIII (Kis = 2.1, 5.4, and 15 nM, respectively). Metolazone (0.3 and 1 mg/kg) induces fluid loss and enhances captopril-induced decreases in...

7-Methylguanosine is a methylated form of the purine nucleoside guanosine (Cay-27702). It is an RNA modification that is present in the 5'-terminal cap of mRNA, where it promotes translation, as well as in tRNA, where it stabilizes the tRNA structure. 7-Methylguanosine has been used as a substrate to measure the...

6beta-Naltrexol (Cay-15896) is an analytical reference material that is structurally categorized as an opioid. It is the major metabolite of naltrexone (Cay-ISO60192, Cay-15520). Unlike naltrexone, which acts as a µ-receptor antagonist or inverse agonist, 6beta-naltrexol is a neutral opioid antagonist....

Procyanidin B2 is a phenol and a dimer of (-)-epicatechin (Cay-11807) that has been found in apple pomace and has diverse biological activities. It inhibits MCF-7 breast cancer cell proliferation (IC50 = 19.2 µM). Procyanidin B2 scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) and superoxide anion radicals...