- Search results for Cay15986
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13 products were found matching "Cay15986"!
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Item number: Cay15896-5
6beta-Naltrexol (Cay-15896) is an analytical reference material that is structurally categorized as an opioid. It is the major metabolite of naltrexone (Cay-ISO60192, Cay-15520). Unlike naltrexone, which acts as a µ-receptor antagonist or inverse agonist, 6beta-naltrexol is a neutral opioid antagonist....
Keywords: | 6beta-hydroxy Naltrexone, (5alpha,6beta)-17-(cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol |
Application: | Analytical reference material, Opioid, Major naltrexone metabolite |
CAS | 49625-89-0 |
MW: | 343.4 D |
From 109.00€
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Item number: Cay19586-1
7-ethoxy-4-Methylcoumarin is a fluorophore that has been used to monitor functional activity of cytochrome P450 (CYP)1A1, CYP2B4, and CYP2B6. It demonstrates excitation/emission maxima of 318 and 377 nm, respectively in methanol and 360 and 449 nm, respectively in dealkylase.Formal Name:...
Keywords: | 4-Methyl-7-Ethoxycoumarin, 4-Methylumbelliferone ethyl ether, NSC 60561, 7-ethoxy-4-methyl-2H-1-benzopyran-2-one |
Application: | CYP1A1 / CYP2B4 / CYP2B6 activity monitoring, Fluorophore |
CAS | 87-05-8 |
MW: | 204.2 D |
From 158.00€
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Item number: Cay18659-50
4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid (Cay-18263) in many non-mammalian organisms, including bacteria and fungi. Folates, like tetrahydrofolic acid, have critical roles in the metabolism of nucleic acid precursors and several amino acids, as well as...
Keywords: | p-Aminobenzoic Acid, PABA, 4-amino-benzoic acid, monosodium salt |
Application: | Tetrahydrofolic acid synthesis intermediate |
CAS | 555-06-6 |
MW: | 159.1 D |
From 50.00€
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Item number: Cay15869-500
Moxalactam is a beta-lactam antibiotic in the cephalosporin class. It is classified as an oxacephem, as oxygen replaces sulfur in position one of the dihydrothiazolidine ring. While moxalactam inhibits most commonly occurring gram positive, gram negative, and anaerobic bacteria, it is ineffective against...
Keywords: | Antibiotic 6059S, Latamoxef, LY 127935,... |
Application: | beta-lactam antibiotic |
CAS | 64953-12-4 |
MW: | 564.4 D |
From 86.00€
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Item number: Cay16598-1
Goat anti-GST (Glutathione-S-Transferase) IgG conjugated to SureLight(TM) APC Antibody: Goat polyclonal anti-GST IgG Dye: SureLight(TM) Allophycocyanin (APC) Excitation max. lambda: 652 nm Emission max. lambda: 657.5 nm Uses: Flow cytometry, Fluorescence-activated cell sorting, Optimized for high-throughput...
Application: | FC, Fluorescence, HTS, TR-FRET |
Host: | Goat |
From 488.00€
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Item number: Cay15988-100
7-Methylguanosine is a methylated form of the purine nucleoside guanosine (Cay-27702). It is an RNA modification that is present in the 5'-terminal cap of mRNA, where it promotes translation, as well as in tRNA, where it stabilizes the tRNA structure. 7-Methylguanosine has been used as a substrate to measure the...
Keywords: | 7-methyl-guanosine |
Application: | 5' terminal cap structure analog, cancer biomarker |
CAS | 20244-86-4 |
MW: | 297.3 D |
From 43.00€
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Item number: Cay15987-10
Metolazone is a thiazide-like diuretic. It inhibits the Na+/Cl- cotransporter (IC50 = 0.3 µM for the rat transporter) and human carbonic anhydrase VII (CAVII), CAXII, and CAXIII (Kis = 2.1, 5.4, and 15 nM, respectively). Metolazone (0.3 and 1 mg/kg) induces fluid loss and enhances captopril-induced decreases in...
Keywords: | SR 720-22, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide |
Application: | Na+-Cl- symport / SLC12A3 inhibitor |
CAS | 17560-51-9 |
MW: | 365.8 D |
From 43.00€
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Item number: Cay15989-500
Lofexidine is an alpha2-adrenergic receptor agonist (Kd = 7.6 nM for rat cerebral cortex membranes) that has transient antihypertensive effects. It is used in managing opioid withdrawal symptoms during detoxification from heroin (Cay-9001543) and methadone.Formal Name:...
Keywords: | 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole, monohydrochloride |
Application: | alpha2b-adrenergic receptor agonist |
CAS | 21498-08-8 |
MW: | 295.6 D |
From 54.00€
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Item number: Cay13986-5
Pirfenidone is an orally bioavailable pyridone derivative with antifibrotic, anti-inflammatory, and antioxidant activities. It inhibits TGF-beta1-stimulated increases in collagen type I, fibronectin, and Hsp47 expression in A549 lung cancer cells in a concentration-dependent manner. Pirfenidone (300 mg/kg per day)...
Keywords: | AMR 69, 5-methyl-1-phenyl-2(1H)-pyridinone |
Application: | Antioxidant, Antiinflammatory |
CAS | 53179-13-8 |
MW: | 185.2 D |
From 60.00€
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Item number: Cay14986-5
Ac-DEVD-AMC is a fluorogenic substrate that can be cleaved specifically by caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.Formal Name:...
Keywords: | Caspase-3 Substrate (Fluorogenic), N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin,... |
Application: | Fluorogenic caspase-3 substrate |
CAS | 169332-61-0 |
MW: | 675.6 D |
From 82.00€
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Item number: Cay16986-5
BYL719 is an inhibitor of phosphoinositide 3-kinase alpha (PI3Kalpha, IC50s = 4.6, 4, and 4.8 nM for wild-type, E545K mutant, and H1047R mutant PI3K, respectively). It is selective for PI3Kalpha over PI3Kbeta, PI3Kdelta, PI3Kgamma, and PI4Kbeta (IC50s = 1,156, 290, 250, and 581 nM, respectively), as well as VPS34,...
Keywords: | Alpelisib, NVP-BYL719,... |
Application: | PI3Kalpha inhibitor |
CAS | 1217486-61-7 |
MW: | 441.5 D |
From 73.00€
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Item number: Cay17986-5
Quizartinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3, Kd = 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases. It inhibits the proliferation of the human leukemia cell line MV4-11, which harbors a homozygous FLT3-ITD mutation, with an IC50 value of...
Keywords: | AC220, N-[5-(1,1-dimethylethyl)-3-isoxazolyl]-N'-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]-urea |
Application: | FLT3 inhibitor |
CAS | 950769-58-1 |
MW: | 560.7 D |
From 39.00€
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