- Search results for Cay14670-10
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22 products were found matching "Cay14670-10"!
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Item number: Cay14674-10
BB-22 (Cay-14099) is synthetic cannabinoid which has been identified in herbal mixtures. It is a quinolinyl cyclohexyl indole with a carboxylate group, abbreviated as QUCHIC. methyl-1-(cyclohexylmethyl)-1H-indole-3-Carboxylate is an analog of BB-22 that lacks the quinoline group. The physiological and toxicological...
Keywords: | methyl ester 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 858515-82-9 |
MW: | 271.4 D |
From 158.00€
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Item number: Cay14675-10
PB-22 (Cay-14096) is synthetic cannabinoid which has been identified in herbal mixtures. It is a quinolinyl pentyl indole with a carboxylate group, abbreviated as QUPIC. 5-fluoro PB-22 (Cay-14095) is a derivative of PB-22 that bears a fluorine atom at the terminal carbon of the pentyl chain....
Keywords: | 1-(5-fluoropentyl)-1H-indole-3-carboxylic acid, methyl ester |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 2460738-70-7 |
MW: | 263.3 D |
From 158.00€
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Item number: Cay14676-10
PB-22 (Cay-14096) is synthetic cannabinoid that has been identified in herbal mixtures. It is a quinolinyl pentyl indole with a carboxylate group, abbreviated as QUPIC. methy-1-pentyl-1H-indole-3-Carboxylate is an analog of PB-22 that lacks the quinoline group. The physiological and toxicological properties of this...
Keywords: | 1-pentyl-1H-indole-3-carboxylic acid, methyl ester |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 1338925-20-4 |
MW: | 245.3 D |
From 158.00€
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Item number: Cay14673-10
G protein-coupled estrogen receptor (GPER), or GPR30, specifically binds natural and man-made estrogens. It is thought to be involved in estrogen-sensitive cancers. GPER knockout mice are fertile, although they exhibit thymic atrophy, impaired glucose tolerance, and altered bone growth. G-15 is a cell-permeable...
Keywords: | (3aS,4R,9bR)-4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline |
Application: | GPER / GPR30 antagonist |
CAS | 1161002-05-6 |
MW: | 370.2 D |
From 84.00€
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Item number: Cay14678-10
SET domain-containing protein 7/9 (SET7/9) is a histone methyltransferase that monomethylates lysine 4 of histone H3, which generates a specific tag for epigenetic transcriptional activation. It plays a role in the transcriptional activation of tumor suppressor p53 in response to DNA damage as well as the...
Keywords: | (-)-PFI-2,... |
Application: | Cell-permeable SET7/9 inhibitor |
CAS | 1627607-87-7 |
MW: | 536 D |
From 77.00€
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Item number: Cay10467-100
Eicosapentaenoic acid (EPA, Cay-90110) is an omega-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils. EPA is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases. (±)5(6)-DiHETE is a possible metabolite...
Keywords: | (±)5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid |
Application: | Metabolic studies |
CAS | 845673-97-4 |
MW: | 336.5 D |
From 141.00€
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Item number: Cay14610-1
(±)-Thalidomide is an immunomodulatory compound with diverse biological activities, including anticancer, anti-inflammatory, and teratogenic properties. It prevents polymorphonuclear leukocyte (PMN) chemotaxis when used at concentrations of 1, 10, and 100 µg/ml. (±)-Thalidomide increases IL-2-induced proliferation...
Keywords: | N-Phthaloylglutamimide, NSC 527179, NSC 66847, 2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
Application: | E3 UB ligase inhibitor |
CAS | 50-35-1 |
MW: | 258.2 D |
From 77.00€
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Item number: Cay14010-1
PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Keywords: | Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 363-24-6 |
MW: | 352.5 D |
From 35.00€
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Item number: Cay14176-10
Idarubicin is a 4-demethoxy analog of the leukemia therapeutic daunorubicin (Cay-14159). Both are anthracycline antibiotics which intercalate in DNA and inhibit topoisomerase II, resulting in cancer cell cytotoxicity at low concentrations (IC50 = 20-120 nM for idarubicin). Idarubicin is effective in combination...
Keywords: | 4-Demethoxydaunorubicin, 4-DMD, NSC 256439,... |
Application: | TOP2 inhibitor |
CAS | 57852-57-0 |
MW: | 534 D |
From 48.00€
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Item number: Cay14876-10
HA-14-1 is a small molecule that binds the surface pocket of Bcl-2 proteins (IC50 = ~ 9 µM) and induces apoptosis by interfering with its interaction with the Bak peptide and activating Apaf-1 and caspase-9 and -3. It can also bind to the antiapoptotic Bcl-2 proteins Bcl-xl and Bcl-W. HA-14-1 has been shown to...
Keywords: | (alphaR,4R)-rel-2-amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid, ethyl ester |
Application: | Apoptosis inducer |
CAS | 927635-64-1 |
MW: | 409.2 D |
From 43.00€
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Item number: Cay14976-10
TAS 301 (10 µM) impedes Ca2+ mobilization and Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) activation that inhibits vascular smooth muscle cell (VSMC) proliferation in vitro. At a concentration of 10 µM, TAS 301 also inhibits platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of...
Keywords: | 3-[bis(4-methoxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one |
Application: | Smooth muscle cell migration & proliferation inhibitor |
CAS | 193620-69-8 |
MW: | 357.4 D |
From 43.00€
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Item number: Cay14687-100
JWH 019 N-(5-hydroxyhexyl) metabolite-d5 (Cay-14687) is intended for use as an internal standard for the quantification of JWH 019 N-(5-hydroxyhexyl) metabolite (Cay-14814) by GC- or LC-MS. Cannabimimetic indoles, including certain JWH compounds, have been identified in herbal blends. JWH 018, a potent agonist of...
Keywords: | (1-(5-hydroxyhexyl)-1H-indol-3-yl-2,4,5,6,7-d5)(naphthalen-1-yl)methanone |
Application: | Analytical reference standard, GC-MS, LC-MS internal standard, quantification, exp. JWH 019 metabolite |
CAS | 2747917-84-4 |
MW: | 376.5 D |
From 339.00€
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