7 products were found matching "AG-40A-0002-C050"!

The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and...

Human IL-33 (amino acids 112-270) is fused at the C-terminus to a His-tag. Activates human ST2-dependent NF-kappaB pathway. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell...

The extracellular domain of mouse GITRL (amino acids 45-173) is fused at the N-terminus to a FLAG(R)-tag. Induces GITR-mediated NF-kappaB activation in HEK 293 cells. Liquid. 0.2µm-filtered solution in 10mM glycine, pH 10.0. GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC),...

Recognizes mouse resistin. Detects a band of about 14kDa by Western blot. Does not cross-react with human resistin. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules...

Human MFAP4 (amino acids 1-255) is fused at the C-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS. Microfibril-associated protein 4 (MFAP4) was initially identified as a gene commonly deleted in the contiguous Smith-Magenis syndrome (SMS) gene. MFAP4 was identified as growth factor to support...

(3 x 50µg). Mouse GITR (amino acids 20-152) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T...

Mouse ANGPTL3 (amino acids 17-455) is fused at the N-terminus to a FLAG(R)-tag. Liquid. 0.2µm-filtered solution in PBS. ANGPTL3 (Angiopoietin-like protein 3) regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.