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Meclofenamate (sodium salt)
Item number: Cay70550-1000
Meclofenamate is a time-dependent, non-specific competitive inhibitor of COX-1 and -2. The IC50 values for inhibition of human recombinant COX-1 and -2 are 1.5 and 9.7 µM, respectively for instantaneous inhibition. However, the IC50 is much lower if pre-incubated with the enzyme.Formal Name:...
| Keywords: | Meclofenamic Acid, 2-[(2,6-dichloro-3-methylphenyl)amino]-benzoic acid, monosodium salt |
| Application: | COX inhibitor |
| CAS | 6385-02-0 |
| MW: | 318.1 D |
From 44.00€
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Aconitase Assay Kit
Item number: Cay705502-96
Aconitase is an iron-sulfur protein containing a [Fe4S4]2+ cluster that catalyzes the stereospecific isomerization of citrate to isocitrate via cis-aconitate. Whereas exposure of aconitase to oxidants renders the enzyme inactive, loss of aconitase activity in cells or in biological samples treated with pro-oxidants...
| Keywords: | ACO2, Aconitase, EC=4.2.1.3, Citrate hydro-lyase, Aconitate hydratase, mitochondrial |
| Application: | Aconitase detection |
428.00€
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CPHPC
Item number: Cay75500-5
CPHPC is an inhibitor of the protein-protein interaction between serum amyloid P (SAP) and amyloid fibrils (IC50 = 0.9 µM). It also crosslinks with pentameric SAP in the plasma to form a decameric complex, which is eliminated via hepatic clearance. As plasma and amyloid deposits of SAP exist in a dynamic...
| Keywords: | GSK2315698, Ro 63-8695, 1,1'-(1,6-dioxo-1,6-hexanediyl)bis-D-proline |
| Application: | Divalent serum amyloid A protein crosslinker |
| CAS | 224624-80-0 |
| MW: | 340.4 D |
From 84.00€
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