7 products were found matching "Cay16160"!
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Acetyl-Coenzyme A (sodium salt)
Item number: Cay16160-10
Acetyl-coenzyme A (acetyl-CoA), the thioester of CoA (Cay-16147) and acetic acid, is a pivotal molecule in biological systems. Foremost, it serves as a source of carbon for the Krebs cycle, for the synthesis of fatty acids, and for isoprenoid-based protein modifications. Acetyl-CoA also serves as an intermediate in...
| Keywords: | Acetyl-CoA, S-acetate coenzyme A, trisodium salt |
| Application: | Krebs cycle intermediate |
| CAS | 102029-73-2 |
| MW: | 878.5 D |
From 44.00€
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2-Hydroxypropyl-beta-cyclodextrin
Item number: Cay16169-10
2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring...
| Keywords: | HP-beta-CD, 2-hydroxypropyl ethers beta-cyclodextrin |
| Application: | Solubility enhancer |
| CAS | 128446-35-5 |
| MW: | 1541.6 D |
From 44.00€
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ISX-9
Item number: Cay16165-10
ISX-9 is a small molecule inducer of adult neural stem cell differentiation both in vitro and in vivo. At 2.5-20 µM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer...
| Keywords: | Isoxazole 9, Neuronal Differentiation Inducer III, N-cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide |
| Application: | Adult neural stem cell differentiation inducer |
| CAS | 832115-62-5 |
| MW: | 234.3 D |
From 43.00€
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GSA 10
Item number: Cay16164-10
Smoothened (SMO) is a cell surface receptor that, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors. GSA 10 is a quinolinecarboxamide derivative that acts as an agonist of SMO. By acting at SMO, GSA 10 has been shown to promote the differentiation of...
| Keywords: | 4-[[(1-hexyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl)carbonyl]amino]-benzoic acid, propyl ester |
| Application: | SMO agonist |
| CAS | 300833-95-8 |
| MW: | 450.5 D |
From 114.00€
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LY411575
Item number: Cay16162-10
gamma-Secretase is a multi-subunit aspartyl protease that regulates signaling pathways by proteolytically cleaving substrates, abrogating or releasing signaling molecules. One well-known substrate of this enzyme is Notch, a transmembrane receptor that plays a key role in cell fate decisions including cell...
| Keywords: | N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-alphaS-hydr... |
| Application: | gamma-?secretase inhibitor |
| CAS | 209984-57-6 |
| MW: | 479.5 D |
From 50.00€
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MAZ51
Item number: Cay16168-10
The VEGF receptors (VEGFRs) mediate signaling leading to angiogenesis, with VEGFR3 (FLT4), activated by VEGF isoforms VEGFC and VEGFD, primarily expressed on lymphatic endothelial cells and directing lymphangiogenesis. MAZ51 is an indolinone that selectively antagonizes the activation of VEGFR3 by VEGFC (IC50 = 1...
| Keywords: | 3-[[4-(dimethylamino)-1-naphthalenyl]methylene]-1,3-dihydro-2H-indol-2-one |
| Application: | VEGFR-3 VEGF-C antagonist |
| CAS | 163655-37-6 |
| MW: | 314.4 D |
From 66.00€
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PluriSln 1
Item number: Cay16161-50
PluriSln 1 is an N-acyl phenylhydrazine derivative that inhibits stearoyl-CoA desaturase, a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (hPSCs). PluriSln 1 can selectively induce ER stress, attenuate protein synthesis, and induce apoptosis in hPSCs (EC50 = 2 µM) while sparing...
| Keywords: | N'-phenyl-hydrazine-Isonicotinic acid, NSC 14613, 2-phenylhydrazide-4-pyridinecarboxylic acid |
| Application: | Stearoyl-CoA desaturase inhibitor, HPSC apoptosis inducer |
| CAS | 91396-88-2 |
| MW: | 213.2 D |
From 84.00€
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