- Search results for Cay11599
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4 products were found matching "Cay11599"!
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Item number: Cay11599-10
MEK kinases are central components of diverse intracellular signaling pathways. MEK1 and MEK2 specifically act downstream of growth factor receptors and the proto-oncogenes Ras and Raf to activate ERK1 and ERK2, often leading to an increase in cell proliferation. AZD 6244 is a potent, highly selective inhibitor of...
Keywords: | ARRY-142886, CL 1,040, NSC 741O78, Selumetinib,... |
Application: | MEK1 / MEK2 inhibitor |
CAS | 606143-52-6 |
MW: | 457.7 D |
From 43.00€
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Item number: Cay15559-5
Mdivi 1 is a mitochondrial division inhibitor. It inhibits the GTPase activity of yeast, but not human, dynamin-1 (Dnm1, IC50 = ~1-10 µM for the recombinant yeast enzyme) and human dynamin-related protein 1 (DRP1) in A549 lung cancer cells when used at a concentration of 50 µM. Mdivi 1 (50 µM) inhibits mitochondrial...
Keywords: | Mitochondrial Division Inhibitor 1, 3-(2,4-dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone |
Application: | Mitochondrial division inhibitor, dynamin inhibitor |
CAS | 338967-87-6 |
MW: | 353.2 D |
From 66.00€
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Item number: Cay15599-5
SNC 80 is a selective nonpeptide agonist of the delta-opioid receptor (Ki = 0.18 nM, IC50 = 2.73 nM) that is over 2,000-fold less effective at the µ-opioid receptor. It effectively activates µ/delta receptor heteromers (EC50 = 52.8 nM) but not kappa/delta or µ/kappa heteromers. SNC 80 has antinociceptive as well as...
Keywords: | NIH 10815, 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-benzamide |
Application: | delta-opioid receptor agonist |
CAS | 156727-74-1 |
MW: | 449.6 D |
From 92.00€
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Item number: Cay15999-10
Etifoxine is a positive allosteric modulator of alpha1beta2gamma2 and alpha1beta3gamma2 subunit-containing GABAA receptors. It selectively increases GABA-induced currents in X. laevis oocytes expressing alpha1beta2gamma2 or alpha1beta3gamma2 over alpha1beta1gamma2 subunit-containing receptors at 20 µM. Etifoxine...
Keywords: | Etafenoxine, HOE 36-801, 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3, 1-benzoxazin-2-amine |
Application: | Anxiolytic, Positive allosteric GABA(A) receptor modulator |
CAS | 21715-46-8 |
MW: | 300.8 D |
From 115.00€
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