- Search results for Cay13111
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11 products were found matching "Cay13111"!
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Item number: Cay13111-5
AZD 4547 is a selective inhibitor of the fibroblast growth factor receptor (FGFR) tyrosine kinase with IC50 values of 0.2, 2.5, and 1.8 nM for FGFR1, 2, and 3, respectively. It displays weaker activity against FGFR4 (IC50 = 165 nM), VEGFR2 (IC50 = 24 nM), and a panel of other tyrosine and serine/theronine kinases...
Keywords: | rel-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-benzamide |
Application: | FGFR inhibitor |
CAS | 1035270-39-3 |
MW: | 463.6 D |
From 147.00€
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Item number: Cay11133-1
One of the first organisms in which quorum sensing was observed were Myxobacteria, a group of gram-negative bacteria, found mainly in soil and also common to marine and freshwater systems. The cellular membranes of autotrophic bacteria contain mono-unsaturated fatty acids. The specific composition and abundance of...
Keywords: | 2-hexadecenoic acid |
Application: | Bioactive lipid assays |
CAS | 2825-68-5 |
MW: | 254.4 D |
From 84.00€
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Item number: Cay13333-1
Bisindolylmaleimide VIII (BIM VIII) is a selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. This compound exhibits some degree of PKC isozyme specificity with preference for PKCalpha over PKCbetaI, PKCbetaII, PKCgamma, or PKCepsilon (IC50s = 53,...
Keywords: | BIM VIII, Ro 31-7549, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, acetate |
Application: | PKC inhibitor |
CAS | 138516-31-1 |
MW: | 458.5 D |
From 68.00€
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Item number: Cay13311-1
Gö 6983 inhibits several isoforms of protein kinase C (PKC, IC50 = 7, 7, 6, 10, 60, and 20,000 nM for PKCalpha, PKCbeta, PKCgamma, PKCdelta, PKCzeta, and PKCµ, respectively). It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction.Formal Name:...
Keywords: | 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
Application: | PKC inhibitor |
CAS | 133053-19-7 |
MW: | 442.5 D |
From 60.00€
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Item number: Cay11311-5
4-acetoxy DiPT (acetate) (Cay-11311) is an analytical reference standard categorized as a tryptamine. 4-acetoxy DiPT induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential. 4-acetoxy DiPT substitutes for DOM (Cay-11145, Cay-15703) in a two-lever drug discrimination test. 4-acetoxy DiPT...
Keywords: | 4-acetoxy-N,N-Diisopropyltryptamine, Ipracetin, 3-[2-[bis(1-methylethyl)amino]ethyl]-1H-indol-4-ol, 4-acetate, monoacetate |
Application: | Analytical reference standard, Tryptamine |
CAS | 2749435-22-9 |
MW: | 362.5 D |
From 266.00€
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Item number: Cay13331-5
bpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 38 nM). It also inhibits the vascular endothelial PTP, PTP-beta (IC50 = 343 nM), and PTP-1beta (IC50 = 920 nM). At 0.1 mM, bpV(phen) inhibits SH2 domain-containing...
Keywords: | Bisperoxovanadium(phen), Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V),... |
Application: | PTP inhibitor |
CAS | 171202-16-7 |
MW: | 404.3 D |
From 49.00€
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Item number: Cay11331-1
The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin E is an epoxide-containing analog of cytochalasin B (Cay-11328) which potently and selectively...
Keywords: | NSC 175151,... |
Application: | Actin polymerisation inhibitor |
CAS | 36011-19-5 |
MW: | 495.6 D |
From 90.00€
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Item number: Cay13118-1
Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces...
Keywords: | 1,1-Dimethylbiguanide hydrochloride, N,N-dimethyl-imidodicarbonimidic diamide, monohydrochloride |
Application: | AMPK activator |
CAS | 1115-70-4 |
MW: | 165.6 D |
From 31.00€
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Item number: Cay13114-1
7-hydroxy Mitragynine (Cay-13114) is an analytical reference standard categorized as an opioid. 7-hydroxy Mitragynine has been found in M. speciosa (Kratom in Thai) and is also an active metabolite of mitragynine (Cay-18567, Cay-11151)., This product is intended for research and forensic applications.Formal Name:...
Keywords: | 7-Hydroxymitragynine, 9-methoxy Corynantheidine Hydroxyindolenine,... |
Application: | Analytical reference standard, Opioid |
CAS | 174418-82-7 |
MW: | 414.5 D |
824.00€
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Item number: Cay13115-1
UR-144 N-(2-chloropentyl) analog is a synthetic cannabinoid which differs from the parent compound, UR-144 (Cay-11502), by the addition of chloride to the 2 position of the pentyl chain. The physiological and toxicological properties of this compound have not been studied. This product is intended for forensic and...
Keywords: | (1-(2-chloropentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone |
Application: | Analytical reference standard, Synthetic cannabinoid analog |
CAS | 2365471-32-3 |
MW: | 345.9 D |
From 235.00€
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Item number: Cay13117-1
UR-144 N-(4-chloropentyl) analog is a synthetic cannabinoid that differs from the parent compound, UR-144 (Cay-ISO60055), by the addition of chloride to the 4 position of the pentyl chain. The physiological and toxicological properties of this compound have not been studied. This product is intended for forensic and...
Keywords: | (1-(4-chloropentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone |
Application: | Analytical reference standard, Synthetic cannabinoid analog |
CAS | 2365471-17-4 |
MW: | 345.9 D |
From 235.00€
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