- Search results for Cay14490
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19 products were found matching "Cay14490"!
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Item number: Cay14490-100
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in linking protein complexes to acetylated nucleosomes, thereby controlling chromatin...
Keywords: | L16, ATAD2, ANCCA, ANCCA, ATPase family AAA domain-containing protein 2, ATPase family AAA domain-containing protein 2,... |
Application: | Estrogen and androgen receptor coactivator |
Expressed in: | E.coli |
MW: | 43,1 kD |
481.00€
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Item number: Cay14990-50
Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. In human ocular tissue, it comprises 2.4% of the COX products formed. When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.Formal Name:...
Keywords: | PGE3, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 802-31-3 |
MW: | 350.5 D |
From 189.00€
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Item number: Cay14900-5
Nitracaine is a structural analog of dimethocaine, a local anesthetic that inhibits dopamine reuptake through the dopamine transporter and is characterized by reinforcing behavioral effects in rhesus monkey similar to that of cocaine. The physiological and toxicological properties of this compound are not known....
Keywords: | 3-(diethylamino)-2,2-dimethylpropyl 4-nitrobenzoate |
Application: | Analytical reference standard, Structural dimethocaine analog |
CAS | 1648893-21-3 |
MW: | 308.4 D |
From 84.00€
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Item number: Cay11490-25
Survivin, a member of the inhibitor of apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in many types of cancer. YM-155 is a novel small molecule that suppresses transactivation of survivin through direct binding to its promoter. It selectively suppresses expression of...
Keywords: | Sepantronium bromide, 4,9-dihydro-1-(2-methoxyethyl)2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium,... |
Application: | Survivin suppressor |
CAS | 781661-94-7 |
MW: | 443.3 D |
From 48.00€
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Item number: Cay14499-50
Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
Keywords: | 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo... |
Application: | Antibiotic |
CAS | 3513-03-9 |
MW: | 458.9 D |
From 54.00€
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Item number: Cay14498-10
Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo, providing the metabolic energy to drive metabolic pumps and serving as a coenzyme in a wide array of enzymatic reactions. ATP is a substrate for kinases involved in cell signaling and of adenylate cyclases that produce...
Keywords: | ATP, NSC 20268, adenosine 5'-(tetrahydrogen triphosphate), disodium salt |
Application: | Kinase / adenylate cyclase substrate, Metabolic studies |
CAS | 987-65-5 |
MW: | 551.1 D |
From 77.00€
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Item number: Cay14496-10
N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity,...
Keywords: | GVS-111, Noopept, SGS 111, 1-(2-phenylacetyl)-L-prolyl-glycine, ethyl ester |
Application: | Analytical reference standard, Synthetic dipeptide, Nootropic, Antioxidant, Antiinflammatory |
CAS | 157115-85-0 |
MW: | 318.4 D |
From 84.00€
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Item number: Cay14497-10
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to...
Keywords: | N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide |
Application: | FAAH inhibitor |
CAS | 681136-29-8 |
MW: | 365.5 D |
From 98.00€
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Item number: Cay14493-100
Macrophage Migration Inhibitory Factor (MIF) is a small, pro-inflammatory cytokine. MIF signaling is important in septic shock, arthritis, colitis, and cardiovascular diseases. MIF counteracts glucocorticoid signaling, which would otherwise inhibit inflammation. Secreted MIF binds to CD74 receptors, which then...
Keywords: | MIF, MIF, GIF, MIF, GIF, GLIF, L-dopachrome isomerase, L-dopachrome isomerase, L-dopachrome tautomerase, L-dopachrome... |
Application: | Enzyme activity, WB |
595.00€
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Item number: Cay14491-100
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in linking protein complexes to acetylated nucleosomes, thereby controlling chromatin...
Keywords: | Bromodomain containing protein 7, Protein CELTIX-1 |
Application: | Binding studies |
Expressed in: | E.coli |
Origin: | human |
MW: | 42,2 kD |
642.00€
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Item number: Cay14492-100
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling...
Keywords: | BRD6, Bromodomain testis-specific protein, Cancer/testis antigen 9, CT9, RING3-like protein |
Application: | Binding assays |
Expressed in: | E. coli |
MW: | 68,7 kD |
465.00€
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Item number: Cay14194-50
Chloroquine is an aminoquinoline that is an inhibitor of autophagy and has antimalarial, anti-inflammatory, anticancer, and antiviral activities. Chloroquine inhibits autophagosome-lysosome fusion in HeLa cells when used at a concentration of 100 µM. It is active against the chloroquine-sensitive GC03 strain of P....
Keywords: | DL-Chloroquine, NSC 14050, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine, diphosphate |
Application: | Autophagy inhibitor, antimalarial |
CAS | 50-63-5 |
MW: | 515.9 D |
From 84.00€
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