19 products were found matching "Cay14490"!

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ATAD2 bromodomain (human recombinant)
ATAD2 bromodomain (human recombinant)

Item number: Cay14490-100

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in linking protein complexes to acetylated nucleosomes, thereby controlling chromatin...
Keywords: L16, ATAD2, ANCCA, ANCCA, ATPase family AAA domain-containing protein 2, ATPase family AAA domain-containing protein 2,...
Application: Estrogen and androgen receptor coactivator
Expressed in: E.coli
MW: 43,1 kD
481.00€ *
Review
Prostaglandin E3
Prostaglandin E3

Item number: Cay14990-50

Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. In human ocular tissue, it comprises 2.4% of the COX products formed. When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.Formal Name:...
Keywords: PGE3, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid
Application: Bioactive lipid assays
CAS 802-31-3
MW: 350.5 D
From 189.00€ *
Review
Nitracaine
Nitracaine

Item number: Cay14900-5

Nitracaine is a structural analog of dimethocaine, a local anesthetic that inhibits dopamine reuptake through the dopamine transporter and is characterized by reinforcing behavioral effects in rhesus monkey similar to that of cocaine. The physiological and toxicological properties of this compound are not known....
Keywords: 3-(diethylamino)-2,2-dimethylpropyl 4-nitrobenzoate
Application: Analytical reference standard, Structural dimethocaine analog
CAS 1648893-21-3
MW: 308.4 D
From 84.00€ *
Review
YM-155
YM-155

Item number: Cay11490-25

Survivin, a member of the inhibitor of apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in many types of cancer. YM-155 is a novel small molecule that suppresses transactivation of survivin through direct binding to its promoter. It selectively suppresses expression of...
Keywords: Sepantronium bromide, 4,9-dihydro-1-(2-methoxyethyl)2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium,...
Application: Survivin suppressor
CAS 781661-94-7
MW: 443.3 D
From 48.00€ *
Review
Blasticidin S (hydrochloride)
Blasticidin S (hydrochloride)

Item number: Cay14499-50

Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
Keywords: 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo...
Application: Antibiotic
CAS 3513-03-9
MW: 458.9 D
From 54.00€ *
Review
Adenosine 5'-triphosphate (sodium salt)
Adenosine 5'-triphosphate (sodium salt)

Item number: Cay14498-10

Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo, providing the metabolic energy to drive metabolic pumps and serving as a coenzyme in a wide array of enzymatic reactions. ATP is a substrate for kinases involved in cell signaling and of adenylate cyclases that produce...
Keywords: ATP, NSC 20268, adenosine 5'-(tetrahydrogen triphosphate), disodium salt
Application: Kinase / adenylate cyclase substrate, Metabolic studies
CAS 987-65-5
MW: 551.1 D
From 77.00€ *
Review
N-Phenylacetyl-L-Prolylglycine ethyl ester
N-Phenylacetyl-L-Prolylglycine ethyl ester

Item number: Cay14496-10

N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity,...
Keywords: GVS-111, Noopept, SGS 111, 1-(2-phenylacetyl)-L-prolyl-glycine, ethyl ester
Application: Analytical reference standard, Synthetic dipeptide, Nootropic, Antioxidant, Antiinflammatory
CAS 157115-85-0
MW: 318.4 D
From 84.00€ *
Review
JNJ-1661010
JNJ-1661010

Item number: Cay14497-10

Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to...
Keywords: N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide
Application: FAAH inhibitor
CAS 681136-29-8
MW: 365.5 D
From 98.00€ *
Review
MIF (human recombinant)
MIF (human recombinant)

Item number: Cay14493-100

Macrophage Migration Inhibitory Factor (MIF) is a small, pro-inflammatory cytokine. MIF signaling is important in septic shock, arthritis, colitis, and cardiovascular diseases. MIF counteracts glucocorticoid signaling, which would otherwise inhibit inflammation. Secreted MIF binds to CD74 receptors, which then...
Keywords: MIF, MIF, GIF, MIF, GIF, GLIF, L-dopachrome isomerase, L-dopachrome isomerase, L-dopachrome tautomerase, L-dopachrome...
Application: Enzyme activity, WB
595.00€ *
Review
BRD7 bromodomain (human, recombinant)
BRD7 bromodomain (human, recombinant)

Item number: Cay14491-100

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in linking protein complexes to acetylated nucleosomes, thereby controlling chromatin...
Keywords: Bromodomain containing protein 7, Protein CELTIX-1
Application: Binding studies
Expressed in: E.coli
Origin: human
MW: 42,2 kD
642.00€ *
Review
BRDT bromodomains 1 and 2 (human, recombinant)
BRDT bromodomains 1 and 2 (human, recombinant)

Item number: Cay14492-100

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling...
Keywords: BRD6, Bromodomain testis-specific protein, Cancer/testis antigen 9, CT9, RING3-like protein
Application: Binding assays
Expressed in: E. coli
MW: 68,7 kD
465.00€ *
Review
Chloroquine (phosphate)
Chloroquine (phosphate)

Item number: Cay14194-50

Chloroquine is an aminoquinoline that is an inhibitor of autophagy and has antimalarial, anti-inflammatory, anticancer, and antiviral activities. Chloroquine inhibits autophagosome-lysosome fusion in HeLa cells when used at a concentration of 100 µM. It is active against the chloroquine-sensitive GC03 strain of P....
Keywords: DL-Chloroquine, NSC 14050, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine, diphosphate
Application: Autophagy inhibitor, antimalarial
CAS 50-63-5
MW: 515.9 D
From 84.00€ *
Review
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