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Item number: Cay17132-10

ARN-509 is an antagonist of the androgen receptor (IC50 = 16 nM). It binds the receptor but does not cause nuclear localization or DNA binding. ARN-509 is orally bioavailable and, at 30 mg/kg/d, suppresses tumor growth in a mouse model of castration-resistant prostate cancer. This compound can be used to study...

Keywords:	JNJ-56021927,...
Application:	Androgen receptor antagonist
CAS	956104-40-8
MW:	477.4 D

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