- Search results for Cay11912
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4 products were found matching "Cay11912"!
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Item number: Cay11912-10
AP-18 is a channel blocker which reversibly inhibits TRPA1 (IC50s = 3.1 and 4.5 µM, human and mouse, respectively). It has minimal effect on TRPV1-4 or TRPM8. AP-18 has been used to study TRPA1 signaling in mice and rats as well as in vitro.Formal Name: 4-(4-chlorophenyl)-3-methyl-3-buten-2-one, oxime. CAS Number:...
Keywords: | 4-(4-chlorophenyl)-3-methyl-3-buten-2-one, oxime |
Application: | TRPA1 inhibitor |
CAS | 55224-94-7 |
MW: | 209.7 D |
From 77.00€
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Item number: Cay19912-1
AZD 3965 is a potent inhibitor of monocarboxylate transporter 1 (MCT1, Ki = 1.6 nM), killing tumor cells that are reliant on glycolysis by blocking lactate transport. It displays six-fold selectivity for MCT1 over MCT2 and is without effect against MCT4 at 10 µM. AZD 3965 increases intratumor lactate levels and...
Keywords: | 5-[[(4S)-4-hydroxy-4-methyl-2-isoxazolidinyl]carbonyl]-3-methyl-1-(1-methylethyl)-6-[[5-methyl-3-(trifluoromethyl)-1H-pyra... |
Application: | SLC16A1 inhibitor |
CAS | 1448671-31-5 |
MW: | 515.5 D |
From 65.00€
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Item number: Cay19112-10
KT172 is a non-selective inhibitor of diacylglycerol lipase alpha (DAGLalpha) and DAGLbeta. It inhibits DAGL-mediated hydrolysis of 1-stearoyl-2-arachidonoylglycerol (Cay-10008650) in HEK293T cell membranes expressing recombinant DAGLalpha or DAGLbeta (IC50s = 140 and 60 nM, respectively). KT172 also inhibits...
Keywords: | [4-(2'-methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl][2-(phenylmethyl)-1-piperidinyl]-methanone |
Application: | Diacylglycerol lipase alpha (DAGL) alpha / beta inhibitor |
CAS | 1402612-56-9 |
MW: | 452.6 D |
From 130.00€
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Item number: Cay19122-5
NBI 31772 is a nonpeptide ligand that releases insulin-like growth factor-1 (IGF-1) from its binding protein (IGFBP, Kis = 1-24 nM for the six human subtypes of IGFBP). As the released IGF-1 is biologically active, NBI 31772 is used to assess the role of IGF-1 in cells and animals, including in neuron survival,...
Keywords: | 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid |
Application: | IGFBP ligand |
CAS | 374620-70-9 |
MW: | 341.3 D |
From 43.00€
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